Crude and adjusted marginal means or effects of studied factors on EEV and PEV Counts
| Variable . | EEVs (n = 631) . | PEVs (n = 632) . | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Crude . | Adjusted* † . | Crude . | Adjusted . | |||||||||
| Mean/effect . | 95% CI . | P . | Mean/effect . | 95% CI . | P . | Mean/effect . | 95% CI . | P . | Mean/effect . | 95% CI . | P . | |
| Processing factors | ||||||||||||
| Filter | <.0001 | <.0001 | ||||||||||
| Fe-WBf | 477.3 | (324.5 to 630.0) | 73.4 | (–310.3 to 457.1) | ||||||||
| M-WBf | 1098.2 | (861.4 to 1329.8) | 16.0 | (–767.5 to 799.4) | ||||||||
| Fr-WBf | 1095.6 | (786.3 to 1410.0) | 4555.3 | (3967.0 to 5143.5) | ||||||||
| M-RBCf | 129.4 | (–456.8 to 715.6) | 33.5 | (–1439.2 to 1506.2) | ||||||||
| Fe-RBCf | 438.9 | (299.4 to 578.4) | 25.1 | (–325.3 to 375.5) | ||||||||
| Preparation time, h | 36.8 | (18.2 to 55.5) | <.001 | 25.4 | (6.2 to 44.6) | .01 | 119.2 | (67.5 to 171.0) | <.0001 | |||
| Product factors | ||||||||||||
| Storage time, d | 45.5 | (35.8 to 55.3) | <.0001 | 42.4 | (27.9 to 56.9) | <.0001 | 5.4 | (–23.5 to 34.2) | .7146 | |||
| Erythrocyte count, ×1012/L | 75.6 | (–80.0 to 231.1) | .34 | −381.2 | (–815.0 to 52.6) | .0849 | ||||||
| Platelet count, ×109/L | 6.2 | (3.0 to 9.5) | <.001 | 67.1 | (59.7 to 74.6) | <.0001 | 67.1 | (59.7 to 74.6) | <.0001 | |||
| Volume, mL | 3.7 | (–0.5 to 7.9) | .08 | 16.1 | (4.5 to 27.6) | .0067 | ||||||
| Donor factors | ||||||||||||
| Donor age, y | −1.3 | (–7.5 to 5.0) | .69 | 6.9 | (–10.5 to 24.3) | .44 | ||||||
| Donor sex | .20 | .01 | ||||||||||
| Female | 671.5 | (523.0 to 820.0) | 1128.3 | (716.0 to 1540.6) | ||||||||
| Male | 547.4 | (431.7 to 663.1) | 435.6 | (114.6 to 756.7) | ||||||||
| Blood group | <.0001 | <.001 | ||||||||||
| O | 509.7 | (378.0 to 641.4) | 638.2 | (270.0 to 1006.3) | ||||||||
| A | 558.3 | (426.2 to 690.5) | 439.1 | (69.7 to 808.5) | ||||||||
| B | 1273.8 | (911.9 to 1635.7) | 2748.4 | (1736.8 to 3760.0) | ||||||||
| AB | 1897.3 | (1032.1 to 2762.5) | 2574.4 | (156.2 to 4992.6) | ||||||||
| Rh(D) | .48 | .68 | ||||||||||
| Positive | 607.2 | (595.1 to 705.4) | 444.8 | (718.4 to 992.0) | ||||||||
| Negative | 510.4 | (333.4 to 759.9) | −135.6 | (559.8 to 1255.2) | ||||||||
| Erythrocyte count, ×1012/L | 224.8 | (–16.1 to 465.6) | .07 | 264.9 | (40.4 to 489.4) | .02 | −712.8 | (–1383.5 to −42.1) | .04 | |||
| White blood cell count, ×109/L | 6.0 | (–47.3 to 59.3) | .83 | 97.0 | (–51.4 to 245.3) | .20 | ||||||
| Variable . | EEVs (n = 631) . | PEVs (n = 632) . | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Crude . | Adjusted* † . | Crude . | Adjusted . | |||||||||
| Mean/effect . | 95% CI . | P . | Mean/effect . | 95% CI . | P . | Mean/effect . | 95% CI . | P . | Mean/effect . | 95% CI . | P . | |
| Processing factors | ||||||||||||
| Filter | <.0001 | <.0001 | ||||||||||
| Fe-WBf | 477.3 | (324.5 to 630.0) | 73.4 | (–310.3 to 457.1) | ||||||||
| M-WBf | 1098.2 | (861.4 to 1329.8) | 16.0 | (–767.5 to 799.4) | ||||||||
| Fr-WBf | 1095.6 | (786.3 to 1410.0) | 4555.3 | (3967.0 to 5143.5) | ||||||||
| M-RBCf | 129.4 | (–456.8 to 715.6) | 33.5 | (–1439.2 to 1506.2) | ||||||||
| Fe-RBCf | 438.9 | (299.4 to 578.4) | 25.1 | (–325.3 to 375.5) | ||||||||
| Preparation time, h | 36.8 | (18.2 to 55.5) | <.001 | 25.4 | (6.2 to 44.6) | .01 | 119.2 | (67.5 to 171.0) | <.0001 | |||
| Product factors | ||||||||||||
| Storage time, d | 45.5 | (35.8 to 55.3) | <.0001 | 42.4 | (27.9 to 56.9) | <.0001 | 5.4 | (–23.5 to 34.2) | .7146 | |||
| Erythrocyte count, ×1012/L | 75.6 | (–80.0 to 231.1) | .34 | −381.2 | (–815.0 to 52.6) | .0849 | ||||||
| Platelet count, ×109/L | 6.2 | (3.0 to 9.5) | <.001 | 67.1 | (59.7 to 74.6) | <.0001 | 67.1 | (59.7 to 74.6) | <.0001 | |||
| Volume, mL | 3.7 | (–0.5 to 7.9) | .08 | 16.1 | (4.5 to 27.6) | .0067 | ||||||
| Donor factors | ||||||||||||
| Donor age, y | −1.3 | (–7.5 to 5.0) | .69 | 6.9 | (–10.5 to 24.3) | .44 | ||||||
| Donor sex | .20 | .01 | ||||||||||
| Female | 671.5 | (523.0 to 820.0) | 1128.3 | (716.0 to 1540.6) | ||||||||
| Male | 547.4 | (431.7 to 663.1) | 435.6 | (114.6 to 756.7) | ||||||||
| Blood group | <.0001 | <.001 | ||||||||||
| O | 509.7 | (378.0 to 641.4) | 638.2 | (270.0 to 1006.3) | ||||||||
| A | 558.3 | (426.2 to 690.5) | 439.1 | (69.7 to 808.5) | ||||||||
| B | 1273.8 | (911.9 to 1635.7) | 2748.4 | (1736.8 to 3760.0) | ||||||||
| AB | 1897.3 | (1032.1 to 2762.5) | 2574.4 | (156.2 to 4992.6) | ||||||||
| Rh(D) | .48 | .68 | ||||||||||
| Positive | 607.2 | (595.1 to 705.4) | 444.8 | (718.4 to 992.0) | ||||||||
| Negative | 510.4 | (333.4 to 759.9) | −135.6 | (559.8 to 1255.2) | ||||||||
| Erythrocyte count, ×1012/L | 224.8 | (–16.1 to 465.6) | .07 | 264.9 | (40.4 to 489.4) | .02 | −712.8 | (–1383.5 to −42.1) | .04 | |||
| White blood cell count, ×109/L | 6.0 | (–47.3 to 59.3) | .83 | 97.0 | (–51.4 to 245.3) | .20 | ||||||
Data are reported as mean (95% CI): marginal or predicted means for categorical variables and the predicted effect for a 1-unit change of the covariate for quantitative variables.
Interaction term between product platelet count and filter type was significant (P = .0003). Platelet count effect for filter type RZ2000, 126.6; LXT, 178.4; Fr, −104.8; NPT, 62.1; and OptiPure, 6.0.
Interaction term between donor blood group and storage time was significant (P = .0003). Storage time effect for blood group O, 0; A, −6.3; B, 27.3; and AB, 58.0.