Median, IQR, and number of patients of the most extreme laboratory values during the admission for patients included in the sample
| Value (reference range) . | Minimal COVID-19 . | Severe COVID-19 . | MIS-C . | |||
|---|---|---|---|---|---|---|
| Median (IQR) . | n . | Median (IQR) . | n . | Median (IQR) . | n . | |
| Coagulation | ||||||
| D-dimer, highest (0.27-0.60 μg/mL FEU) | — | 2.53 (0.6-20.5) | 11 | 4.93 (3.42-5.75) | 17 | |
| PT, highest (11.6-13.8 s) | — | 16 (13.2-31) | 11 | 15.4 (14.4-17.4) | 18 | |
| PTT, highest (22-36 s) | — | 52.4 (37.5-78.8) | 11 | 31.8 (28.4-36.6) | 17 | |
| Fibrinogen (172-471 mg/dL) | ||||||
| Lowest | — | 297 (239-332) | 10 | 297 (237-370) | 17 | |
| Highest | — | 488 (305-890) | 10 | 572 (484-721) | 17 | |
| Chemistry | ||||||
| AST, highest (10-30 U/L) | 59 (40-72) | 17 | 123 (54-627) | 11 | 88 (63-104) | 18 |
| Creatinine, highest (0.3-0.8 mg/dL) | 0.4 (0.3-0.8) | 19 | 0.7 (0.3-2.3) | 11 | 0.6 (0.5-1.3) | 18 |
| GFR, minimum (mL/min) | 193 (108-221) | 18 | 111 (40-243) | 11 | 136 (65-182) | 18 |
| BUN, highest (7-18 mg/dL) | 12 (7-23) | 19 | 23 (13-34) | 11 | 21.5 (16-39) | 18 |
| Hematology | ||||||
| Platelets (150-400 K/μL) | ||||||
| Lowest | 220 (127-295) | 21 | 128 (78-165) | 11 | 141 (121-194) | 18 |
| Highest | 414 (165-363) | 21 | 311 (223-347) | 11 | 414 (275-483) | 18 |
| Hemoglobin, lowest (12-16 g/dL) | 9.2 (7.4-11.9) | 21 | 8.9 (6.7-11.1) | 11 | 8.9 (7.9-10) | 18 |
| Inflammatory and cardiac | ||||||
| Ferritin, highest (10.0-82.0 ng/ml) | — | 419 (164-2747) | 10 | 806 (665-1162) | 17 | |
| CRP, highest (0-0.9 mg/dL) | 13.9 (3.1-18.3) | 11 | 30.3 (7-34.9) | 11 | 23.7 (19-34.6) | 18 |
| ESR, highest (0-20 mm/h) | — | – | 59 (43-82) | 17 | ||
| BNP, highest (≤100 pg/mL) | — | 307 (46-542) | 8 | 997 (510-1242) | 17 | |
| Troponin, highest (<0.3 ng/ml) | — | 0.13 (0.02-1.79) | 9 | 0.39 (0.07-1.34) | 17 | |
| IL-8 | 10 (5-16.6) | 15 | 32.7 (12.3-124) | 11 | 37.3 (20.4-56.7) | 17 |
| Interferon-γ | 14 (4-150) | 15 | 54 (12-100) | 11 | 191 (41-481) | 17 |
| sC5b9 (≤257 ng/mL) | 392 (244-622) | 21 | 646 (203-728) | 11 | 630 (359-932) | 18 |
| Value (reference range) . | Minimal COVID-19 . | Severe COVID-19 . | MIS-C . | |||
|---|---|---|---|---|---|---|
| Median (IQR) . | n . | Median (IQR) . | n . | Median (IQR) . | n . | |
| Coagulation | ||||||
| D-dimer, highest (0.27-0.60 μg/mL FEU) | — | 2.53 (0.6-20.5) | 11 | 4.93 (3.42-5.75) | 17 | |
| PT, highest (11.6-13.8 s) | — | 16 (13.2-31) | 11 | 15.4 (14.4-17.4) | 18 | |
| PTT, highest (22-36 s) | — | 52.4 (37.5-78.8) | 11 | 31.8 (28.4-36.6) | 17 | |
| Fibrinogen (172-471 mg/dL) | ||||||
| Lowest | — | 297 (239-332) | 10 | 297 (237-370) | 17 | |
| Highest | — | 488 (305-890) | 10 | 572 (484-721) | 17 | |
| Chemistry | ||||||
| AST, highest (10-30 U/L) | 59 (40-72) | 17 | 123 (54-627) | 11 | 88 (63-104) | 18 |
| Creatinine, highest (0.3-0.8 mg/dL) | 0.4 (0.3-0.8) | 19 | 0.7 (0.3-2.3) | 11 | 0.6 (0.5-1.3) | 18 |
| GFR, minimum (mL/min) | 193 (108-221) | 18 | 111 (40-243) | 11 | 136 (65-182) | 18 |
| BUN, highest (7-18 mg/dL) | 12 (7-23) | 19 | 23 (13-34) | 11 | 21.5 (16-39) | 18 |
| Hematology | ||||||
| Platelets (150-400 K/μL) | ||||||
| Lowest | 220 (127-295) | 21 | 128 (78-165) | 11 | 141 (121-194) | 18 |
| Highest | 414 (165-363) | 21 | 311 (223-347) | 11 | 414 (275-483) | 18 |
| Hemoglobin, lowest (12-16 g/dL) | 9.2 (7.4-11.9) | 21 | 8.9 (6.7-11.1) | 11 | 8.9 (7.9-10) | 18 |
| Inflammatory and cardiac | ||||||
| Ferritin, highest (10.0-82.0 ng/ml) | — | 419 (164-2747) | 10 | 806 (665-1162) | 17 | |
| CRP, highest (0-0.9 mg/dL) | 13.9 (3.1-18.3) | 11 | 30.3 (7-34.9) | 11 | 23.7 (19-34.6) | 18 |
| ESR, highest (0-20 mm/h) | — | – | 59 (43-82) | 17 | ||
| BNP, highest (≤100 pg/mL) | — | 307 (46-542) | 8 | 997 (510-1242) | 17 | |
| Troponin, highest (<0.3 ng/ml) | — | 0.13 (0.02-1.79) | 9 | 0.39 (0.07-1.34) | 17 | |
| IL-8 | 10 (5-16.6) | 15 | 32.7 (12.3-124) | 11 | 37.3 (20.4-56.7) | 17 |
| Interferon-γ | 14 (4-150) | 15 | 54 (12-100) | 11 | 191 (41-481) | 17 |
| sC5b9 (≤257 ng/mL) | 392 (244-622) | 21 | 646 (203-728) | 11 | 630 (359-932) | 18 |
Results were not reported if >50% of data were missing.
AST, aspartate transaminase; BNP, B-type natriuretic peptide; CRP, C-reactive protein; ESR, erythrocyte sedimentation rate; FEU, fibrinogen equivalent units; PT, prothrombin time; PTT, partial thromboplastin time.