Table 2.

Multivariate analysis of CMB presence and clinical characteristics of patients with ITP

CharacteristicUnivariate Poisson analysisMultivariate Poisson analysis
Incidence rate ratioPIncidence rate ratioP
Disease duration, each additional month 1.00 (1.00, 1.01) 2.06 × 10−5*** 1.01 (1.00, 1.01) 7.11 × 10−6*** 
Platelet count, at time of MRI 0.992 (0.988, 0.996) 2.71 × 10−4*** 0.994 (0.989, 1.00) .029* 
Platelet count, low point 0.879 (0.824, 0.939) 1.28 × 10−4*** 0.867 (0.786, 0.957) .005** 
Number of treatments, each additional treatment 1.10 (1.03, 1.16) .003** 0.928 (0.831, 1.04) .187 
SMOG (≥2), organ 3.27 (1.86, 5.76) 4.10 × 10−5*** 2.32 (1.10, 4.90) .028* 
SMOG (≥2), mucosal 2.40 (1.29, 4.48) .006** 1.09 (0.444, 2.65) .857 
SMOG (≥2), skin 0.837 (0.469, 1.49) .547 Not included — 
Age, each additional year 0.995 (0.980, 1.01) .534 1.01 (0.990, 1.03) .350 
Sex, male 1.63 (1.02, 2.60) .042* 0.786 (0.382, 1.62) .513 
CharacteristicUnivariate Poisson analysisMultivariate Poisson analysis
Incidence rate ratioPIncidence rate ratioP
Disease duration, each additional month 1.00 (1.00, 1.01) 2.06 × 10−5*** 1.01 (1.00, 1.01) 7.11 × 10−6*** 
Platelet count, at time of MRI 0.992 (0.988, 0.996) 2.71 × 10−4*** 0.994 (0.989, 1.00) .029* 
Platelet count, low point 0.879 (0.824, 0.939) 1.28 × 10−4*** 0.867 (0.786, 0.957) .005** 
Number of treatments, each additional treatment 1.10 (1.03, 1.16) .003** 0.928 (0.831, 1.04) .187 
SMOG (≥2), organ 3.27 (1.86, 5.76) 4.10 × 10−5*** 2.32 (1.10, 4.90) .028* 
SMOG (≥2), mucosal 2.40 (1.29, 4.48) .006** 1.09 (0.444, 2.65) .857 
SMOG (≥2), skin 0.837 (0.469, 1.49) .547 Not included — 
Age, each additional year 0.995 (0.980, 1.01) .534 1.01 (0.990, 1.03) .350 
Sex, male 1.63 (1.02, 2.60) .042* 0.786 (0.382, 1.62) .513 
***

Significant at an α level of .001.

**

Significant at an α level of .01.

*

Significant at an α level of .05.

Bleeding score were factored into 2 groups: a score of 0 or 1 or a score of 2 or greater. Scores were not available for 8 patients.

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