Consensus criteria proposed by Ferrara et al for defining patients unfit for intensive chemotherapy
| Fulfillment of at least one criterion suggests patient is unfit for intensive induction chemotherapy. |
| Advanced age (over 75 y) |
| Severe cardiac comorbidity |
| Severe pulmonary comorbidity |
| Severe renal comorbidity |
| Severe hepatic comorbidity |
| Active infection resistant to anti-infective therapy |
| Cognitive impairment |
| Low performance status (ECOG functional scale) |
| Any other comorbidity that the physician judges to be incompatible with chemotherapy |
| Fulfillment of at least one criterion suggests patient is unfit for intensive induction chemotherapy. |
| Advanced age (over 75 y) |
| Severe cardiac comorbidity |
| Severe pulmonary comorbidity |
| Severe renal comorbidity |
| Severe hepatic comorbidity |
| Active infection resistant to anti-infective therapy |
| Cognitive impairment |
| Low performance status (ECOG functional scale) |
| Any other comorbidity that the physician judges to be incompatible with chemotherapy |
Adapted from Ferrara et al.6
ECOG, Eastern Cooperative Oncology Group.