Events during induction therapy
| Event . | Patients, n . | % . |
|---|---|---|
| Fever at presentation | 75 | 37.5 |
| Presumptive site of infection | ||
| Lung (pneumonia) | 10 | 5.0 |
| Skin (cellulitis) | 3 | 1.5 |
| Bone (osteomyelitis) | 1 | 0.5 |
| Viral infection (hepatitis A, varicella) | 2 | 1.0 |
| Gastrointestinal tract (colitis, gastroenteritis) | 3 | 1.5 |
| Fever and/or infection during induction | 135 | 67.5 |
| Presumptive site of infection | ||
| Lung (pneumonia) | 23 | 11.5 |
| Skin (cellulitis) | 9 | 4.5 |
| Central venous catheter | 2 | 1.0 |
| Perianal region | 4 | 2.0 |
| Gastrointestinal tract | 8 | 4.0 |
| Urinary tract | 1 | 0.5 |
| Bacteremia | ||
| At presentation | 11 | 5.5 |
| During induction | 50 | 25.0 |
| Fungal infection (suspected pulmonary and/or sinus) (median time, 16 days; range, 1-30) | 18 | 9.0 |
| Thrombosis | ||
| Cerebral | 2 | 1.0 |
| Deep venous thrombosis | 1 | 0.5 |
| Pancreatitis | 3 | 1.5 |
| Hypertension | 3 | 1.5 |
| Mucositis grade 3 | 5 | 2.5 |
| Seizures | 2 | 1.0 |
| Bleeding (pulmonary, melena, and hematuria) | 5 | 2.5 |
| Mortality (early deaths) | 3 | 1.5 |
| Event . | Patients, n . | % . |
|---|---|---|
| Fever at presentation | 75 | 37.5 |
| Presumptive site of infection | ||
| Lung (pneumonia) | 10 | 5.0 |
| Skin (cellulitis) | 3 | 1.5 |
| Bone (osteomyelitis) | 1 | 0.5 |
| Viral infection (hepatitis A, varicella) | 2 | 1.0 |
| Gastrointestinal tract (colitis, gastroenteritis) | 3 | 1.5 |
| Fever and/or infection during induction | 135 | 67.5 |
| Presumptive site of infection | ||
| Lung (pneumonia) | 23 | 11.5 |
| Skin (cellulitis) | 9 | 4.5 |
| Central venous catheter | 2 | 1.0 |
| Perianal region | 4 | 2.0 |
| Gastrointestinal tract | 8 | 4.0 |
| Urinary tract | 1 | 0.5 |
| Bacteremia | ||
| At presentation | 11 | 5.5 |
| During induction | 50 | 25.0 |
| Fungal infection (suspected pulmonary and/or sinus) (median time, 16 days; range, 1-30) | 18 | 9.0 |
| Thrombosis | ||
| Cerebral | 2 | 1.0 |
| Deep venous thrombosis | 1 | 0.5 |
| Pancreatitis | 3 | 1.5 |
| Hypertension | 3 | 1.5 |
| Mucositis grade 3 | 5 | 2.5 |
| Seizures | 2 | 1.0 |
| Bleeding (pulmonary, melena, and hematuria) | 5 | 2.5 |
| Mortality (early deaths) | 3 | 1.5 |