Distribution of candidate prognostic biomarkers for PTS
| Biomarker . | PTS negative (n = 52) . | PTS positive (n = 27) . | P . |
|---|---|---|---|
| 6 wk after diagnosis of DVT | |||
| IL-6, pg/mL | 0.68 (0.32-1.24) | 0.66 (0.34-2.63) | .336 |
| IL-8, pg/mL | 4.55 (3.14-6.18) | 3.97 (2.96-8.97) | .741 |
| IL-10, pg/mL | 0.49 (0.25-0.89) | 0.58 (0.39-0.79) | .589 |
| VEGF-1, pg/mL | 40.54 (26.89-63.1) | 40.52 (26.96-60.58) | .869 |
| CRP, mg/dL* | 0.03 (0.01-0.21) | 0.05 (0.01-0.15) | .682 |
| SAA, mg/L* | 0.98 (0.44-2.6) | 1.34 (0.83-3.62) | .208 |
| VCAM-1, ng/mL | 412.6 (316.73-535.84) | 393.34 (306.02-492.66) | .620 |
| ICAM-1, ng/mL | 327.95 (272.7-417.52) | 311.3 (259.04-405.75) | .532 |
| 3 mo after diagnosis of DVT | |||
| IL-6, pg/mL | 0.57 (0.31-1.2) | 0.65 (0.39-1.62) | .314 |
| IL-8, pg/mL | 4.62 (3.09-7.35) | 5 (3.16-6.51) | .714 |
| IL-10, pg/mL | 0.47 (0.24-0.82) | 0.52 (0.35-0.95) | .171 |
| VEGF-1, pg/mL | 45.31 (31.2-58.2) | 37.11 (3.1-63.2) | .447 |
| CRP, mg/dL* | 0.28 (0.09-1.35) | 0.46 (0.26-1.32) | .319 |
| SAA, mg/L* | 0.8 (0.33-1.81) | 1.44 (0.53-2.21) | .113 |
| VCAM-1, ng/mL | 366.27 (303.1-446.21) | 391.95 (30.1-608.5) | .420 |
| ICAM-1, ng/mL | 290.78 (233.68-367.22) | 290.57 (239.03-454.15) | .605 |
| Biomarker . | PTS negative (n = 52) . | PTS positive (n = 27) . | P . |
|---|---|---|---|
| 6 wk after diagnosis of DVT | |||
| IL-6, pg/mL | 0.68 (0.32-1.24) | 0.66 (0.34-2.63) | .336 |
| IL-8, pg/mL | 4.55 (3.14-6.18) | 3.97 (2.96-8.97) | .741 |
| IL-10, pg/mL | 0.49 (0.25-0.89) | 0.58 (0.39-0.79) | .589 |
| VEGF-1, pg/mL | 40.54 (26.89-63.1) | 40.52 (26.96-60.58) | .869 |
| CRP, mg/dL* | 0.03 (0.01-0.21) | 0.05 (0.01-0.15) | .682 |
| SAA, mg/L* | 0.98 (0.44-2.6) | 1.34 (0.83-3.62) | .208 |
| VCAM-1, ng/mL | 412.6 (316.73-535.84) | 393.34 (306.02-492.66) | .620 |
| ICAM-1, ng/mL | 327.95 (272.7-417.52) | 311.3 (259.04-405.75) | .532 |
| 3 mo after diagnosis of DVT | |||
| IL-6, pg/mL | 0.57 (0.31-1.2) | 0.65 (0.39-1.62) | .314 |
| IL-8, pg/mL | 4.62 (3.09-7.35) | 5 (3.16-6.51) | .714 |
| IL-10, pg/mL | 0.47 (0.24-0.82) | 0.52 (0.35-0.95) | .171 |
| VEGF-1, pg/mL | 45.31 (31.2-58.2) | 37.11 (3.1-63.2) | .447 |
| CRP, mg/dL* | 0.28 (0.09-1.35) | 0.46 (0.26-1.32) | .319 |
| SAA, mg/L* | 0.8 (0.33-1.81) | 1.44 (0.53-2.21) | .113 |
| VCAM-1, ng/mL | 366.27 (303.1-446.21) | 391.95 (30.1-608.5) | .420 |
| ICAM-1, ng/mL | 290.78 (233.68-367.22) | 290.57 (239.03-454.15) | .605 |
All data are presented as median (interquartile range).
PTS negative has 51 patients and PTS positive has 26 patients because of 1 patient with undetectable values.