Table 3.

Survival analyses for differences in time-to-event (years) by first-line management

SurvivalNo. (%)EventsMedian OS or EFS (95% CI)6-year OS or EFS (95% CI)P
OS      
 All patients 123 10 NR 0.93 (0.88-0.99) .024 
 Active surveillance 58 (47) NR 0.91 (0.81-1.00)  
 Surgical resection 51 (41) NR 1.00 (1.00-1.00)  
 Systemic treatment 14 (11) NR 0.76 (0.56-1.00)  
EFS      
 All patients 123 37 9.1 (7.7-NR) 0.69 (0.59-0.79) .013 
 Active surveillance 58 (47) 17 7.2 (6.8-NR) 0.65 (0.51-0.83)  
 Surgical resection 51 (41) 12 NR (12.8-NR) 0.74 (0.62-0.90)  
 Systemic treatment 14 (11) 7.3 (1.8-NR) 0.62 (0.40-0.95)  
SurvivalNo. (%)EventsMedian OS or EFS (95% CI)6-year OS or EFS (95% CI)P
OS      
 All patients 123 10 NR 0.93 (0.88-0.99) .024 
 Active surveillance 58 (47) NR 0.91 (0.81-1.00)  
 Surgical resection 51 (41) NR 1.00 (1.00-1.00)  
 Systemic treatment 14 (11) NR 0.76 (0.56-1.00)  
EFS      
 All patients 123 37 9.1 (7.7-NR) 0.69 (0.59-0.79) .013 
 Active surveillance 58 (47) 17 7.2 (6.8-NR) 0.65 (0.51-0.83)  
 Surgical resection 51 (41) 12 NR (12.8-NR) 0.74 (0.62-0.90)  
 Systemic treatment 14 (11) 7.3 (1.8-NR) 0.62 (0.40-0.95)  

P values correspond to Kaplan-Meier log-rank test.

NR, not reached.

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