Patient characteristics and ORs with 95% CIs of selection to AHCT within 18 mo of diagnosis among stage IB+ MCL patients up to 65 y of age diagnosed in Sweden between January 2000 and June 2014
Variable . | n . | AHCT ≤ 18 mo . | No AHCT ≤ 18 mo . | Unadjusted OR (95% CI) . |
---|---|---|---|---|
Overall (row %) | 369 (100) | 221 (59.9) | 148 (40.1) | |
Marital status at diagnosis (col %) | ||||
Married | 216 (58.5) | 141 (63.8) | 75 (50.7) | 1.00 |
Never married | 68 (18.4) | 39 (17.7) | 29 (19.6) | 0.72 (0.41-1.25) |
Divorced | 73 (19.8) | 37 (16.7) | 36 (24.3) | 0.55 (0.32-0.94) |
Widow(er) | 12 (3.3) | 4 (1.8) | 8 (5.4) | 0.27 (0.08-0.91) |
Highest achieved education level (col %) | ||||
Up to 9 y of schooling | 80 (21.7) | 35 (15.8) | 45 (30.4) | 0.44 (0.26-0.75) |
10 to 12 y of schooling | 175 (47.4) | 112 (50.7) | 63 (42.6) | 1.00 |
>12 y of schooling | 103 (27.9) | 68 (30.8) | 35 (23.7) | 1.09 (0.66-1.82) |
Missing | 11 (3.0) | 6 (2.7) | 5 (3.4) | · |
Country of birth (col %) | ||||
Sweden | 321 (87.0) | 189 (85.5) | 132 (89.2) | 1.00 |
Foreign | 48 (13.0) | 32 (14.5) | 16 (10.8) | 1.40 (0.74-2.65) |
Sex (col %) | ||||
Male | 288 (78.1) | 171 (77.4) | 117 (79.1) | 1.00 |
Female | 81 (21.9) | 50 (22.6) | 31 (20.9) | 1.10 (0.67-1.83) |
CCI (col %) | ||||
0 | 277 (75.1) | 182 (82.4) | 95 (64.2) | 1.00 |
1 | 45 (12.2) | 23 (10.4) | 22 (14.9) | 0.55 (0.29-1.03) |
2+ | 47 (12.7) | 16 (7.2) | 31 (21.0) | 0.27 (0.14-0.52) |
Year of diagnosis (col %) | ||||
2000 to 2004 | 114 (30.9) | 65 (29.4) | 49 (33.1) | 1.00 |
2005 to 2009 | 120 (32.5) | 75 (33.9) | 45 (30.4) | 1.26 (0.74-2.12) |
2010 to 2014 | 135 (36.6) | 81 (36.7) | 54 (36.5) | 1.13 (0.68-1.88) |
Age at diagnosis, y (col %) | ||||
<50 | 51 (13.8) | 39 (17.7) | 12 (8.1) | 1.00 |
50 to 59 | 148 (40.1) | 104 (47.1) | 44 (29.7) | 0.73 (0.35-1.52) |
60 to 65 | 170 (46.1) | 78 (35.3) | 92 (62.2) | 0.26 (0.13-0.53) |
Hospital type where initial diagnosis was made (col %) | ||||
University | 184 (53.4) | 118 (53.4) | 66 (44.6) | 1.00 |
Regional | 127 (34.4) | 67 (30.3) | 60 (40.5) | 0.62 (0.39-0.99) |
Local | 58 (15.7) | 36 (16.3) | 22 (14.9) | 0.92 (0.50-1.68) |
Stage (col %) | ||||
Ann Arbor IB and II | 37 (10.0) | 19 (8.6) | 18 (12.2) | 1.00 |
Ann Arbor III | 49 (13.3) | 33 (14.9) | 16 (10.8) | 1.95 (0.81-4.70) |
Ann Arbor IV | 279 (75.6) | 168 (76.0) | 111 (75.0) | 1.43 (0.72-2.85) |
Missing | 4 (1.1) | 1 (0.5) | 3 (2.0) | |
MCL-specific international prognostic index (col %) | ||||
Low risk (<5.7) | 114 (30.9) | 73 (33.0) | 41 (27.7) | 1.00 |
Intermediate risk (5.7-6.1) | 92 (24.9) | 55 (24.9) | 37 (25.0) | 0.83 (0.47-1.47) |
High risk (>6.1) | 71 (19.2) | 38 (17.2) | 33 (22.3) | 0.65 (0.35-1.18) |
Missing | 92 (24.9) | 55 (24.9) | 37 (25.0) | |
Performance status (col %) | ||||
ECOG 0 to 1 | 332 (90.0) | 207 (93.7) | 125 (84.5) | 1.00 |
ECOG 2 to 4 | 31 (8.4) | 12 (5.4) | 19 (12.8) | 0.38 (0.18-0.81) |
Missing | 6 (1.6) | 2 (0.9) | 4 (2.7) |
Variable . | n . | AHCT ≤ 18 mo . | No AHCT ≤ 18 mo . | Unadjusted OR (95% CI) . |
---|---|---|---|---|
Overall (row %) | 369 (100) | 221 (59.9) | 148 (40.1) | |
Marital status at diagnosis (col %) | ||||
Married | 216 (58.5) | 141 (63.8) | 75 (50.7) | 1.00 |
Never married | 68 (18.4) | 39 (17.7) | 29 (19.6) | 0.72 (0.41-1.25) |
Divorced | 73 (19.8) | 37 (16.7) | 36 (24.3) | 0.55 (0.32-0.94) |
Widow(er) | 12 (3.3) | 4 (1.8) | 8 (5.4) | 0.27 (0.08-0.91) |
Highest achieved education level (col %) | ||||
Up to 9 y of schooling | 80 (21.7) | 35 (15.8) | 45 (30.4) | 0.44 (0.26-0.75) |
10 to 12 y of schooling | 175 (47.4) | 112 (50.7) | 63 (42.6) | 1.00 |
>12 y of schooling | 103 (27.9) | 68 (30.8) | 35 (23.7) | 1.09 (0.66-1.82) |
Missing | 11 (3.0) | 6 (2.7) | 5 (3.4) | · |
Country of birth (col %) | ||||
Sweden | 321 (87.0) | 189 (85.5) | 132 (89.2) | 1.00 |
Foreign | 48 (13.0) | 32 (14.5) | 16 (10.8) | 1.40 (0.74-2.65) |
Sex (col %) | ||||
Male | 288 (78.1) | 171 (77.4) | 117 (79.1) | 1.00 |
Female | 81 (21.9) | 50 (22.6) | 31 (20.9) | 1.10 (0.67-1.83) |
CCI (col %) | ||||
0 | 277 (75.1) | 182 (82.4) | 95 (64.2) | 1.00 |
1 | 45 (12.2) | 23 (10.4) | 22 (14.9) | 0.55 (0.29-1.03) |
2+ | 47 (12.7) | 16 (7.2) | 31 (21.0) | 0.27 (0.14-0.52) |
Year of diagnosis (col %) | ||||
2000 to 2004 | 114 (30.9) | 65 (29.4) | 49 (33.1) | 1.00 |
2005 to 2009 | 120 (32.5) | 75 (33.9) | 45 (30.4) | 1.26 (0.74-2.12) |
2010 to 2014 | 135 (36.6) | 81 (36.7) | 54 (36.5) | 1.13 (0.68-1.88) |
Age at diagnosis, y (col %) | ||||
<50 | 51 (13.8) | 39 (17.7) | 12 (8.1) | 1.00 |
50 to 59 | 148 (40.1) | 104 (47.1) | 44 (29.7) | 0.73 (0.35-1.52) |
60 to 65 | 170 (46.1) | 78 (35.3) | 92 (62.2) | 0.26 (0.13-0.53) |
Hospital type where initial diagnosis was made (col %) | ||||
University | 184 (53.4) | 118 (53.4) | 66 (44.6) | 1.00 |
Regional | 127 (34.4) | 67 (30.3) | 60 (40.5) | 0.62 (0.39-0.99) |
Local | 58 (15.7) | 36 (16.3) | 22 (14.9) | 0.92 (0.50-1.68) |
Stage (col %) | ||||
Ann Arbor IB and II | 37 (10.0) | 19 (8.6) | 18 (12.2) | 1.00 |
Ann Arbor III | 49 (13.3) | 33 (14.9) | 16 (10.8) | 1.95 (0.81-4.70) |
Ann Arbor IV | 279 (75.6) | 168 (76.0) | 111 (75.0) | 1.43 (0.72-2.85) |
Missing | 4 (1.1) | 1 (0.5) | 3 (2.0) | |
MCL-specific international prognostic index (col %) | ||||
Low risk (<5.7) | 114 (30.9) | 73 (33.0) | 41 (27.7) | 1.00 |
Intermediate risk (5.7-6.1) | 92 (24.9) | 55 (24.9) | 37 (25.0) | 0.83 (0.47-1.47) |
High risk (>6.1) | 71 (19.2) | 38 (17.2) | 33 (22.3) | 0.65 (0.35-1.18) |
Missing | 92 (24.9) | 55 (24.9) | 37 (25.0) | |
Performance status (col %) | ||||
ECOG 0 to 1 | 332 (90.0) | 207 (93.7) | 125 (84.5) | 1.00 |
ECOG 2 to 4 | 31 (8.4) | 12 (5.4) | 19 (12.8) | 0.38 (0.18-0.81) |
Missing | 6 (1.6) | 2 (0.9) | 4 (2.7) |
Due to rounding, not all percentages add up to 100. Bold indicates significant exposures associated with a lower chance of being treated with AHCT.
col, column.