HRs with 95% CIs comparing all-cause mortality between AHCT and non-AHCT treated stage IB+ MCL patients diagnosed between January 2000 and June 2014 aged up to 65 y at diagnosis, who were alive 6 mo after diagnosis when follow-up started (n = 363)
| . | . | HR* (95% CI) . | HR† (95% CI) . |
|---|---|---|---|
| Age at diagnosis . | AHCT . | (n = 363) . | (n = 342) . |
| All ages‡ | Yes | 0.45 (0.32-0.63) | 0.58 (0.40-0.85) |
| No | 1.00 | 1.00 | |
| ≤49 y | Yes | 0.43 (0.14-1.35) | 0.38 (0.12-1.19) |
| No | 1.00 | 1.00 | |
| 50 to 59 y | Yes | 0.47 (0.26-0.86) | 0.55 (0.29-1.02) |
| No | 1.00 | 1.00 | |
| 60 to 65 y | Yes | 0.53 (0.34-0.84) | 0.70 (0.43-1.14) |
| No | 1.00 | 1.00 |
| . | . | HR* (95% CI) . | HR† (95% CI) . |
|---|---|---|---|
| Age at diagnosis . | AHCT . | (n = 363) . | (n = 342) . |
| All ages‡ | Yes | 0.45 (0.32-0.63) | 0.58 (0.40-0.85) |
| No | 1.00 | 1.00 | |
| ≤49 y | Yes | 0.43 (0.14-1.35) | 0.38 (0.12-1.19) |
| No | 1.00 | 1.00 | |
| 50 to 59 y | Yes | 0.47 (0.26-0.86) | 0.55 (0.29-1.02) |
| No | 1.00 | 1.00 | |
| 60 to 65 y | Yes | 0.53 (0.34-0.84) | 0.70 (0.43-1.14) |
| No | 1.00 | 1.00 |
Follow-up was restricted to the first 10 y after diagnosis.
From a Cox proportional hazards model treating AHCT as a time-varying exposure (for age-stratified results, an interaction between AHCT and age at diagnosis was included).
From a Cox proportional hazards model as above, adjusted for calendar year of diagnosis (as a restricted cubic spline), sex, civil status, educational level, CCI, stage, and performance status.
A nonsignificant interaction with AHCT and age was seen, indicating that the association between AHCT and all-cause mortality was similar between age groups.