Table 2.

Univariable and multivariable analyses on OS and TTP

UnivariableMultivariable
CharacteristicRisk ratio (range)PCharacteristicRisk ratio (range)P
OS 
 Group 1 vs not 2.5 (1.1-5.6) .02 Group 1 vs not 3.5 (1.5-8.3) .009 
 Age 1.4 (0.22-10.7) .7  
 High-risk disease* 5.51(2.3-11.2) <.0001 High-risk disease* 6.4 (2.8-14.9) <.0001 
 CR post-ASCT 0.83 (0.38-1.76) .6  
 PR/PD vs not 1.9 (0.9-4) .1  
 Received maintenance therapy 2.18 (0.96-4.94) .06  
TTP 
 Group 1 vs not 2.1 (1.01-2.1) .04 Group 1 vs not 2.2 (1.1.-4.6) .03 
 Age 0.26 (0.1-1.5) .12  
 High-risk disease* 2.5 (1.2-5.2) .01 High-risk disease* 2.7 (1.3-5.6) .008 
 CR post-ASCT 1.1 (0.6-2) .8  
 PR/PD vs not 1.8 (0.99-3.4) .06  
 Received maintenance therapy 0.9 (0.5-1.6) .7  
UnivariableMultivariable
CharacteristicRisk ratio (range)PCharacteristicRisk ratio (range)P
OS 
 Group 1 vs not 2.5 (1.1-5.6) .02 Group 1 vs not 3.5 (1.5-8.3) .009 
 Age 1.4 (0.22-10.7) .7  
 High-risk disease* 5.51(2.3-11.2) <.0001 High-risk disease* 6.4 (2.8-14.9) <.0001 
 CR post-ASCT 0.83 (0.38-1.76) .6  
 PR/PD vs not 1.9 (0.9-4) .1  
 Received maintenance therapy 2.18 (0.96-4.94) .06  
TTP 
 Group 1 vs not 2.1 (1.01-2.1) .04 Group 1 vs not 2.2 (1.1.-4.6) .03 
 Age 0.26 (0.1-1.5) .12  
 High-risk disease* 2.5 (1.2-5.2) .01 High-risk disease* 2.7 (1.3-5.6) .008 
 CR post-ASCT 1.1 (0.6-2) .8  
 PR/PD vs not 1.8 (0.99-3.4) .06  
 Received maintenance therapy 0.9 (0.5-1.6) .7  
*

Defined as the presence of t(4;14), del(17/17p), t(14;16), or t(14;20).

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