Table 2.

Multivariable cox regression models for progression to HCoV LRTI

Model 1Model 2Model 3
CovariatesCategoriesHR (95% CI)PHR (95% CI)PHR (95% CI)P
Combined steroid and glucose, mg/dL* Steroid + glucose (>150) vs no steroid 4.73 (1.60-14.0) <.01 4.83 (1.61-14.5) <.01   
 Steroid + glucose (≤150 or unknown) vs no steroid 1.51 (0.58-3.98) .4 1.44 (0.54-3.84) .47   
Transplant number Second or higher HCT vs first HCT 1.56 (0.63-3.90) .34   2.17 (0.92-5.09) .08 
ISI As continuous   1.07 (0.89-1.28) .47 1.14 (0.97-1.34) .12 
Model 1Model 2Model 3
CovariatesCategoriesHR (95% CI)PHR (95% CI)PHR (95% CI)P
Combined steroid and glucose, mg/dL* Steroid + glucose (>150) vs no steroid 4.73 (1.60-14.0) <.01 4.83 (1.61-14.5) <.01   
 Steroid + glucose (≤150 or unknown) vs no steroid 1.51 (0.58-3.98) .4 1.44 (0.54-3.84) .47   
Transplant number Second or higher HCT vs first HCT 1.56 (0.63-3.90) .34   2.17 (0.92-5.09) .08 
ISI As continuous   1.07 (0.89-1.28) .47 1.14 (0.97-1.34) .12 

Total of 25 LRTI events among 279 patients presenting with first HCoV URTI.

*

Systemic steroids in the 2 weeks before HCoV diagnosis.

Using nearest value within 2 weeks before HCoV diagnosis.

At HCoV diagnosis.

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