Multivariate analysis and propensity score matching based on ITT HD-MTX for TT-CNS, PFS, and OS
| . | Multivariate analysis . | PS matching . | IPTW . | |||
|---|---|---|---|---|---|---|
| HR (95% CI) . | P . | HR (95% CI) . | P . | HR (95% CI) . | P . | |
| TT-CNS | 0.72 (0.34-1.54) | .400 | 1 (0.42-2.40) | 1.000 | 0.82 (0.50-1.33) | .418 |
| PFS | 0.93 (0.62-1.40) | .733 | 0.91 (0.57-1.48) | .714 | 0.97 (0.74-1.26) | .801 |
| OS | 0.85 (0.55-1.32) | .473 | 0.94 (0.56-1.55) | .796 | 0.91 (0.68-1.21) | .506 |
| . | Multivariate analysis . | PS matching . | IPTW . | |||
|---|---|---|---|---|---|---|
| HR (95% CI) . | P . | HR (95% CI) . | P . | HR (95% CI) . | P . | |
| TT-CNS | 0.72 (0.34-1.54) | .400 | 1 (0.42-2.40) | 1.000 | 0.82 (0.50-1.33) | .418 |
| PFS | 0.93 (0.62-1.40) | .733 | 0.91 (0.57-1.48) | .714 | 0.97 (0.74-1.26) | .801 |
| OS | 0.85 (0.55-1.32) | .473 | 0.94 (0.56-1.55) | .796 | 0.91 (0.68-1.21) | .506 |
Variables used in the multivariate analysis include age, sex, Eastern Cooperative Oncology Group Performance Status, serum LDH level, number of involved extranodal sites, stage at diagnosis, high-risk extranodal site involvement, and double-expressor status.
HR, hazard ratio; PS, propensity score.