Patient demographics for MDS discovery and validation cohorts and controls
| Demographic characteristic . | Discovery . | Validation . | ||
|---|---|---|---|---|
| MDS (n = 176) . | Controls (n = 29) . | MDS (n = 113) . | Controls (n = 30) . | |
| Age, y | ||||
| Mean | 72.4 | 65.0 | 71.8 | 75 |
| Median | 73 | 64 | 73 | 73 |
| Standard deviation | 8.45 | 4.9 | 7.2 | 5.56 |
| Sex | ||||
| Male | 99 (56.6) | 0 | 61 (54) | 3 (10) |
| Female | 43 (24.6) | 29 (100) | 23 (20.3) | 27 (90) |
| Unknown | 34 (18.9) | 0 | 29 (25.7) | 0 |
| Risk category | ||||
| HR | 14 (8) | NA | 47 (41.6) | NA |
| LR | 162 (92) | NA | 66 (58.4) | NA |
| WHO | ||||
| Single-lineage dysplasia | 9 (5.1) | NA | 4 (3.5) | NA |
| Single-lineage dysplasia, ringed sideroblasts | 30 (17.1) | NA | 36 (31.9) | NA |
| Multilineage dysplasia | 36 (20.4) | NA | 12 (10.6) | NA |
| Multilineage dysplasia, ringed sideroblasts | 14 (8) | NA | 10 (8.8) | NA |
| Excess blasts | 23 (13.1) | NA | 19 (16.8) | NA |
| Not otherwise specified | 58 (33) | NA | 30 (26.6) | NA |
| Unclassified | 6 (3.4) | NA | 2 (1.8) | NA |
| Demographic characteristic . | Discovery . | Validation . | ||
|---|---|---|---|---|
| MDS (n = 176) . | Controls (n = 29) . | MDS (n = 113) . | Controls (n = 30) . | |
| Age, y | ||||
| Mean | 72.4 | 65.0 | 71.8 | 75 |
| Median | 73 | 64 | 73 | 73 |
| Standard deviation | 8.45 | 4.9 | 7.2 | 5.56 |
| Sex | ||||
| Male | 99 (56.6) | 0 | 61 (54) | 3 (10) |
| Female | 43 (24.6) | 29 (100) | 23 (20.3) | 27 (90) |
| Unknown | 34 (18.9) | 0 | 29 (25.7) | 0 |
| Risk category | ||||
| HR | 14 (8) | NA | 47 (41.6) | NA |
| LR | 162 (92) | NA | 66 (58.4) | NA |
| WHO | ||||
| Single-lineage dysplasia | 9 (5.1) | NA | 4 (3.5) | NA |
| Single-lineage dysplasia, ringed sideroblasts | 30 (17.1) | NA | 36 (31.9) | NA |
| Multilineage dysplasia | 36 (20.4) | NA | 12 (10.6) | NA |
| Multilineage dysplasia, ringed sideroblasts | 14 (8) | NA | 10 (8.8) | NA |
| Excess blasts | 23 (13.1) | NA | 19 (16.8) | NA |
| Not otherwise specified | 58 (33) | NA | 30 (26.6) | NA |
| Unclassified | 6 (3.4) | NA | 2 (1.8) | NA |
Data are presented as n (%) unless otherwise specified.
NA, not available; WHO, World Health Organization.