Comparison of red cell exchange procedures pre– and during COVID-19 for patients with goal HbS of <30%, 35% to 45%, and <50%
| . | Goal HbS <30% . | Goal HbS of 35% to 45% . | Goal HbS <50% . | ||||||
|---|---|---|---|---|---|---|---|---|---|
| . | Pre- . | During . | P . | Pre- . | During . | P . | Pre- . | During . | P . |
| Procedures, no | 203 | 224 | 52 | 51 | 41 | 43 | |||
| Mean FCR, %* | 43.4 | 52.4 | <.001 | 48.7 | 54.7 | .022 | 54.8 | 60.6 | .013 |
| No. of procedures with intent to increase hct, % | 115 (51.3) | 14 (27.5) | 9 (20.9) | ||||||
| Total red cell units saved, n | 262 | 54 | 35 | ||||||
| Mean unit no. transfused per RCE* | 6.4 | 5.3 | <.001 | 6.0 | 4.9 | .011 | 4.9 | 4.1 | .021 |
| Mean pretransfusion HbS, %* | 30.1 | 27.9 | .002 | 36.6 | 32.5 | .15 | 41.2 | 41.9 | .65 |
| Mean transfusion interval, d* | 25.9 | 25.4 | .37 | 30.2 | 28.1 | .29 | 32.5 | 32.7 | .84 |
| . | Goal HbS <30% . | Goal HbS of 35% to 45% . | Goal HbS <50% . | ||||||
|---|---|---|---|---|---|---|---|---|---|
| . | Pre- . | During . | P . | Pre- . | During . | P . | Pre- . | During . | P . |
| Procedures, no | 203 | 224 | 52 | 51 | 41 | 43 | |||
| Mean FCR, %* | 43.4 | 52.4 | <.001 | 48.7 | 54.7 | .022 | 54.8 | 60.6 | .013 |
| No. of procedures with intent to increase hct, % | 115 (51.3) | 14 (27.5) | 9 (20.9) | ||||||
| Total red cell units saved, n | 262 | 54 | 35 | ||||||
| Mean unit no. transfused per RCE* | 6.4 | 5.3 | <.001 | 6.0 | 4.9 | .011 | 4.9 | 4.1 | .021 |
| Mean pretransfusion HbS, %* | 30.1 | 27.9 | .002 | 36.6 | 32.5 | .15 | 41.2 | 41.9 | .65 |
| Mean transfusion interval, d* | 25.9 | 25.4 | .37 | 30.2 | 28.1 | .29 | 32.5 | 32.7 | .84 |
Mean of individual averages among 33 patients with a goal HbS < 30%, 8 with a goal HbS of 35% to 45%, and 9 with a goal HbS < 50%.