Evaluation of the independent effect of EASIX score and ferritin level on CRS grades 2 to 4
| . | Parameters . | . | . | . | . | . | . | |
|---|---|---|---|---|---|---|---|---|
| Risk group . | EASIX . | Ferritin . | n* . | Events, n . | CumInc, % . | HR . | 95% CI . | P . |
| High risk | High | Any level | 35 | 26 | 74 | 4.8 | 2.1-11 | <.001 |
| Intermediate risk | Low | High ferritin | 72 | 35 | 49 | 2.3 | 1.02-5 | .04 |
| Low risk | Low | Low ferritin | 34 | 8 | 23 | 1.0 | — | — |
| . | Parameters . | . | . | . | . | . | . | |
|---|---|---|---|---|---|---|---|---|
| Risk group . | EASIX . | Ferritin . | n* . | Events, n . | CumInc, % . | HR . | 95% CI . | P . |
| High risk | High | Any level | 35 | 26 | 74 | 4.8 | 2.1-11 | <.001 |
| Intermediate risk | Low | High ferritin | 72 | 35 | 49 | 2.3 | 1.02-5 | .04 |
| Low risk | Low | Low ferritin | 34 | 8 | 23 | 1.0 | — | — |
High EASIX: levels in the upper quartile (EASIX >4.6); high ferritin: levels above the lowest quartile (ferritin >321 ng/mL); high vs intermediate risk groups: HR, 2.1; 95% CI, 1.3-3.5; P = 0.003. CumInc, cumulative incidence; ECOG, Eastern Cooperative Oncology Group. *Only patients with available ferritin levels were eligible for this analysis.