Time to first therapy and overall survival according to the CLL-IPI risk score among MBL and Rai 0 CLL
| CLL-IPI . | Time to first therapy . | ||||
|---|---|---|---|---|---|
| Estimated 5-y risk . | Estimated 10-y risk . | . | |||
| MBL, % . | Rai 0 CLL, % . | MBL, % . | Rai 0 CLL, % . | MBL vs CLL, P . | |
| Low | 7.1 | 18.6 | 14.9 | 33.7 | .002 |
| Intermediate | 13.4 | 40.8 | 49.0 | 67.7 | <.0001 |
| High | 43.0 | 74.3 | 75.1 | 81.9 | .02 |
| Very high | 0.0 | 57.8 | 0.0 | Not estimable | .09 |
| CLL-IPI | Overall survival | ||||
| Estimated 5-y risk | Estimated 10-y risk | ||||
| MBL, % | Rai 0 CLL, % | MBL, % | Rai 0 CLL, % | MBL vs CLL, P | |
| Low | 95.3 | 97.1 | 82.4 | 80.7 | .98 |
| Intermediate | 94.2 | 89.8 | 72.8 | 67.9 | .55 |
| High | 83.6 | 77.1 | 62.4 | 46.0 | .14 |
| Very high | 75.0 | 26.9 | 75.0 | 13.5 | .36 |
| CLL-IPI . | Time to first therapy . | ||||
|---|---|---|---|---|---|
| Estimated 5-y risk . | Estimated 10-y risk . | . | |||
| MBL, % . | Rai 0 CLL, % . | MBL, % . | Rai 0 CLL, % . | MBL vs CLL, P . | |
| Low | 7.1 | 18.6 | 14.9 | 33.7 | .002 |
| Intermediate | 13.4 | 40.8 | 49.0 | 67.7 | <.0001 |
| High | 43.0 | 74.3 | 75.1 | 81.9 | .02 |
| Very high | 0.0 | 57.8 | 0.0 | Not estimable | .09 |
| CLL-IPI | Overall survival | ||||
| Estimated 5-y risk | Estimated 10-y risk | ||||
| MBL, % | Rai 0 CLL, % | MBL, % | Rai 0 CLL, % | MBL vs CLL, P | |
| Low | 95.3 | 97.1 | 82.4 | 80.7 | .98 |
| Intermediate | 94.2 | 89.8 | 72.8 | 67.9 | .55 |
| High | 83.6 | 77.1 | 62.4 | 46.0 | .14 |
| Very high | 75.0 | 26.9 | 75.0 | 13.5 | .36 |
Values in bold indicate P < .05.