Expression of platelet surface glycoproteins in Jak2Plt−/− mice
| Glycoprotein . | Jak2Plt+/+ . | Jak2Plt−/− . | P . |
|---|---|---|---|
| GPIbα (CD42b) | 1098 ± 448 | 1453 ± 323 | .091 |
| GPIbβ (CD42c) | 3644 ± 1320 | 4650 ± 1486 | .174 |
| GPIX (CD42a) | 5835 ± 2341 | 6114 ± 876 | .757 |
| GPV (CD42d) | 1679 ± 568 | 1926 ± 489 | .369 |
| GPIIIa (CD61, β3 integrin) | 2257 ± 951 | 1971 ± 393 | .444 |
| GPIIa (CD29, β1 integrin) | 11051 ± 7521 | 10762 ± 5917 | .933 |
| GPVI | 1099 ± 240 | 1079 ± 203 | .861 |
| Glycoprotein . | Jak2Plt+/+ . | Jak2Plt−/− . | P . |
|---|---|---|---|
| GPIbα (CD42b) | 1098 ± 448 | 1453 ± 323 | .091 |
| GPIbβ (CD42c) | 3644 ± 1320 | 4650 ± 1486 | .174 |
| GPIX (CD42a) | 5835 ± 2341 | 6114 ± 876 | .757 |
| GPV (CD42d) | 1679 ± 568 | 1926 ± 489 | .369 |
| GPIIIa (CD61, β3 integrin) | 2257 ± 951 | 1971 ± 393 | .444 |
| GPIIa (CD29, β1 integrin) | 11051 ± 7521 | 10762 ± 5917 | .933 |
| GPVI | 1099 ± 240 | 1079 ± 203 | .861 |
Glycoprotein surface expression was measured by flow cytometry on freshly isolated Jak2Plt+/+ and Jak2Plt−/− platelets with fluorescence-labeled antibodies. Data are expressed as mean fluorescence intensity. Results represent mean ± SD and are compared by using the unpaired Student t test (n = 8 in each group).