Univariable Cox model of RFS and OS for molecular subgroups compared with the patients who were DUX4-R as reference group
| Molecular subgroup . | RFS hazard ratio . | P . | OS hazard ratio . | P . |
|---|---|---|---|---|
| BCL2/MYC | 36.4 (7.9, 167.2) | <.001 | 11.3 (3.2, 39.3) | <.001 |
| KMT2A-AFF1 | 7.8 (2.6, 23.3) | <.001 | 6.6 (2.5, 17.1) | <.001 |
| LH/NH | 7.6 (2.6, 22.4) | <.001 | 5.3 (2.0, 14.1) | <.001 |
| Ph-like | 7.5 (2.7, 21.3) | <.001 | 4.9 (1.9, 12.6) | <.001 |
| MEF2D-R | 5.9 (1.6, 21.8) | .009 | 3.0 (0.8, 11.3) | .098 |
| PAX5alt | 4.6 (1.5, 13.7) | .006 | 3.7 (1.4, 10.0) | .010 |
| ZNF384-R/-like | 4.0 (1.1, 14.3) | .031 | 2.6 (0.8, 8.6) | .111 |
| HH | 2.4 (0.7, 8.4) | .154 | 1.0 (0.3, 3.7) | .995 |
| ETV6-RUNX1/-like | 2.0 (0.4, 11.1) | .411 | 0.8 (0.1, 6.7) | .819 |
| PAX5 P80R | 1.5 (0.3, 6.8) | .585 | 1.2 (0.3, 5.1) | .795 |
| TCF3-PBX1 | 1.2 (0.3, 5.5) | .781 | 1.6 (0.5, 5.7) | .429 |
| Molecular subgroup . | RFS hazard ratio . | P . | OS hazard ratio . | P . |
|---|---|---|---|---|
| BCL2/MYC | 36.4 (7.9, 167.2) | <.001 | 11.3 (3.2, 39.3) | <.001 |
| KMT2A-AFF1 | 7.8 (2.6, 23.3) | <.001 | 6.6 (2.5, 17.1) | <.001 |
| LH/NH | 7.6 (2.6, 22.4) | <.001 | 5.3 (2.0, 14.1) | <.001 |
| Ph-like | 7.5 (2.7, 21.3) | <.001 | 4.9 (1.9, 12.6) | <.001 |
| MEF2D-R | 5.9 (1.6, 21.8) | .009 | 3.0 (0.8, 11.3) | .098 |
| PAX5alt | 4.6 (1.5, 13.7) | .006 | 3.7 (1.4, 10.0) | .010 |
| ZNF384-R/-like | 4.0 (1.1, 14.3) | .031 | 2.6 (0.8, 8.6) | .111 |
| HH | 2.4 (0.7, 8.4) | .154 | 1.0 (0.3, 3.7) | .995 |
| ETV6-RUNX1/-like | 2.0 (0.4, 11.1) | .411 | 0.8 (0.1, 6.7) | .819 |
| PAX5 P80R | 1.5 (0.3, 6.8) | .585 | 1.2 (0.3, 5.1) | .795 |
| TCF3-PBX1 | 1.2 (0.3, 5.5) | .781 | 1.6 (0.5, 5.7) | .429 |