Table 1. Patient demographics and... | American Society of Hematology

Table 1.

Patient demographics and clinical characteristics at diagnosis by frontline therapy

	Total (N = 244)		Conventional* (n = 190)		Other (n = 54)
Characteristic	n	%	n	%	n	%	P†
Male sex	113	46.3	85	44.7	28	51.9	.36
Age, y							.004
Median	68		67		73
Range	60 to ≥90		60-88		60 to ≥90
Age category, y
60-69	140	57.4	123	64.7	18	33.3	Ref
70-79	79	32.4	55	28.9	24	44.4	.7
≥80	24	9.8	12	6.3	12	22.2	.002
Stage
Limited (I-II)	89	36.5	70	36.8	19	35.2	Ref
Advanced (III-IV)	155	63.5	120	63.2	35	64.8	.77
B symptoms present	112	45.9	95	50.0	17	31.5	.01
ECOG PS
0-2	214	87.7	166	87.4	48	88.9	Ref
3-4	8	3.3	6	3.2	2	3.7	.03
Unknown/missing data	22	9.0	18	9.4	4	7.4	.65
Impaired ADLs/instrumental ADLs at baseline
No	206	84.4	163	85.9	43	79.6	Ref
Yes	30	12.3	19	10.0	11	20.4	.054
Unknown/missing data	8	3.3	8	4.2	0	0	—
Geriatric syndrome at baseline
No	195	79.9	156	82.1	39	72.2	Ref
Yes	43	17.6	28	14.7	15	27.8	.03
Unknown/missing data	6	2.5	6	3.2	0	0	—
CIRS-G total score
<10	196	80.3	153	80.5	43	79.6	Ref
≥10	48	19.7	37	19.5	11	20.4	.02
Unknown/missing data	0	0	0	0	0	0	—

	Total (N = 244)		Conventional* (n = 190)		Other (n = 54)
Characteristic	n	%	n	%	n	%	P†
Male sex	113	46.3	85	44.7	28	51.9	.36
Age, y							.004
Median	68		67		73
Range	60 to ≥90		60-88		60 to ≥90
Age category, y
60-69	140	57.4	123	64.7	18	33.3	Ref
70-79	79	32.4	55	28.9	24	44.4	.7
≥80	24	9.8	12	6.3	12	22.2	.002
Stage
Limited (I-II)	89	36.5	70	36.8	19	35.2	Ref
Advanced (III-IV)	155	63.5	120	63.2	35	64.8	.77
B symptoms present	112	45.9	95	50.0	17	31.5	.01
ECOG PS
0-2	214	87.7	166	87.4	48	88.9	Ref
3-4	8	3.3	6	3.2	2	3.7	.03
Unknown/missing data	22	9.0	18	9.4	4	7.4	.65
Impaired ADLs/instrumental ADLs at baseline
No	206	84.4	163	85.9	43	79.6	Ref
Yes	30	12.3	19	10.0	11	20.4	.054
Unknown/missing data	8	3.3	8	4.2	0	0	—
Geriatric syndrome at baseline
No	195	79.9	156	82.1	39	72.2	Ref
Yes	43	17.6	28	14.7	15	27.8	.03
Unknown/missing data	6	2.5	6	3.2	0	0	—
CIRS-G total score
<10	196	80.3	153	80.5	43	79.6	Ref
≥10	48	19.7	37	19.5	11	20.4	.02
Unknown/missing data	0	0	0	0	0	0	—

Conventional cHL regimens included AVD, ABVD, BV plus AVD (concurrent or sequential), and Stanford V.

All P values are 2 sided.