Lesion characteristics
| Characteristic . | Overall (N = 299) . | Intent of VLDRT . | |
|---|---|---|---|
| Non-curable (n = 247) . | Potentially curable (n = 52) . | ||
| Previously observed site | 67 (22) | 63 (26) | 4 (7.7) |
| Previous excision to same site | |||
| No | 288 (96) | 236 (95) | 52 (100) |
| Yes | 11 (4) | 11 (5) | 0 (0) |
| VLDRT given to newly diagnosed patient | 88 (29) | 36 (15) | 52 (100) |
| Histology at VLDRT | |||
| FL | 197 (66) | 177 (72) | 20 (38) |
| MZL | 80 (27) | 57 (23) | 23 (44) |
| Low-grade indolent NOS | 22 (7.4) | 13 (5.3) | 9 (17) |
| Stage at time of VLDRT | |||
| I | 99 (33) | 73 (30) | 26 (50) |
| II | 72 (24) | 66 (27) | 6 (12) |
| III | 43 (14) | 43 (17) | 0 (0) |
| IV | 63 (21) | 63 (26) | 0 (0) |
| Localized (cutaneous) | 20 (6.7) | 0 (0) | 20 (38) |
| Multifocal (cutaneous) | 2 (0.7) | 2 (0.8) | 0 (0) |
| Modality of staging at time of VLDRT | |||
| PET/CT | 249 (83) | 199 (81) | 50 (96) |
| CT | 32 (11) | 32 (13) | 0 (0) |
| MRI | 6 (2.0) | 4 (1.6) | 2 (3.8) |
| Mammogram | 2 (0.7) | 2 (0.8) | 0 (0) |
| Clinical | 10 (3.3) | 10 (4.0) | 0 (0) |
| Median pre-VLDRT lesion size, cm* | 2.55 (1.8, 4.1) | 2.60 (1.9, 4.2) | 2.10 (1.2, 3.0) |
| Pre-VLDRT lesion size, cm† | |||
| 0-2 | 79 (30) | 63 (28) | 16 (39) |
| 2-4 | 115 (44) | 94 (42) | 21 (51) |
| 4-6 | 47 (18) | 45 (20) | 2 (4.9) |
| ≥6 | 23 (8.7) | 21 (9.4) | 2 (4.9) |
| Unknown | 35 | 24 | 11 |
| Nodal characteristics of treated fields | |||
| Extranodal | 163 (55) | 123 (50) | 40 (77) |
| Nodal | 122 (41) | 111 (45) | 11 (21) |
| Both | 14 (4.7) | 13 (5.3) | 1 (1.9) |
| Site category | |||
| Skin | 51 (17) | 31 (13) | 20 (38) |
| Head and neck (nodal) | 43 (14) | 41 (17) | 2 (3.8) |
| Eye and orbit | 29 (9.7) | 21 (8.5) | 8 (15) |
| Inguinofemoral | 29 (9.7) | 27 (11) | 2 (3.8) |
| Other | 147 (49) | 127 (51) | 20 (38) |
| Median pre-VLDRT PET highest SUV (IQR)*‡ | 7.3 (5.0-10.5) | 7.8 (5.2-10.8) | 5.0 (3.0-8.1) |
| Pre-VLDRT PET highest SUV† | |||
| 0-5 | 53 (21) | 39 (19) | 14 (29) |
| 5-7.5 | 58 (23) | 50 (25) | 8 (16) |
| 7.5-10 | 41 (16) | 37 (18) | 4 (8.2) |
| 10-15 | 56 (22) | 53 (26) | 3 (6.1) |
| ≥15 | 9 (3.6) | 8 (4.0) | 1 (2.0) |
| Unspecified but less than liver background | 34 (14) | 15 (7.4) | 19 (39) |
| Unknown | 48 | 45 | 3 |
| Characteristic . | Overall (N = 299) . | Intent of VLDRT . | |
|---|---|---|---|
| Non-curable (n = 247) . | Potentially curable (n = 52) . | ||
| Previously observed site | 67 (22) | 63 (26) | 4 (7.7) |
| Previous excision to same site | |||
| No | 288 (96) | 236 (95) | 52 (100) |
| Yes | 11 (4) | 11 (5) | 0 (0) |
| VLDRT given to newly diagnosed patient | 88 (29) | 36 (15) | 52 (100) |
| Histology at VLDRT | |||
| FL | 197 (66) | 177 (72) | 20 (38) |
| MZL | 80 (27) | 57 (23) | 23 (44) |
| Low-grade indolent NOS | 22 (7.4) | 13 (5.3) | 9 (17) |
| Stage at time of VLDRT | |||
| I | 99 (33) | 73 (30) | 26 (50) |
| II | 72 (24) | 66 (27) | 6 (12) |
| III | 43 (14) | 43 (17) | 0 (0) |
| IV | 63 (21) | 63 (26) | 0 (0) |
| Localized (cutaneous) | 20 (6.7) | 0 (0) | 20 (38) |
| Multifocal (cutaneous) | 2 (0.7) | 2 (0.8) | 0 (0) |
| Modality of staging at time of VLDRT | |||
| PET/CT | 249 (83) | 199 (81) | 50 (96) |
| CT | 32 (11) | 32 (13) | 0 (0) |
| MRI | 6 (2.0) | 4 (1.6) | 2 (3.8) |
| Mammogram | 2 (0.7) | 2 (0.8) | 0 (0) |
| Clinical | 10 (3.3) | 10 (4.0) | 0 (0) |
| Median pre-VLDRT lesion size, cm* | 2.55 (1.8, 4.1) | 2.60 (1.9, 4.2) | 2.10 (1.2, 3.0) |
| Pre-VLDRT lesion size, cm† | |||
| 0-2 | 79 (30) | 63 (28) | 16 (39) |
| 2-4 | 115 (44) | 94 (42) | 21 (51) |
| 4-6 | 47 (18) | 45 (20) | 2 (4.9) |
| ≥6 | 23 (8.7) | 21 (9.4) | 2 (4.9) |
| Unknown | 35 | 24 | 11 |
| Nodal characteristics of treated fields | |||
| Extranodal | 163 (55) | 123 (50) | 40 (77) |
| Nodal | 122 (41) | 111 (45) | 11 (21) |
| Both | 14 (4.7) | 13 (5.3) | 1 (1.9) |
| Site category | |||
| Skin | 51 (17) | 31 (13) | 20 (38) |
| Head and neck (nodal) | 43 (14) | 41 (17) | 2 (3.8) |
| Eye and orbit | 29 (9.7) | 21 (8.5) | 8 (15) |
| Inguinofemoral | 29 (9.7) | 27 (11) | 2 (3.8) |
| Other | 147 (49) | 127 (51) | 20 (38) |
| Median pre-VLDRT PET highest SUV (IQR)*‡ | 7.3 (5.0-10.5) | 7.8 (5.2-10.8) | 5.0 (3.0-8.1) |
| Pre-VLDRT PET highest SUV† | |||
| 0-5 | 53 (21) | 39 (19) | 14 (29) |
| 5-7.5 | 58 (23) | 50 (25) | 8 (16) |
| 7.5-10 | 41 (16) | 37 (18) | 4 (8.2) |
| 10-15 | 56 (22) | 53 (26) | 3 (6.1) |
| ≥15 | 9 (3.6) | 8 (4.0) | 1 (2.0) |
| Unspecified but less than liver background | 34 (14) | 15 (7.4) | 19 (39) |
| Unknown | 48 | 45 | 3 |