Prevalence of long-term comorbidities and health problems in patients with APL, overall and by previous randomization group (ATRA-ATO vs ATRA chemotherapy)
| Variable . | Total (N = 161) n (%) . | ATRA-ATO (N = 83) n (%) . | ATRA chemotherapy (N = 78) n (%) . |
|---|---|---|---|
| Hypertension | 53 (32.9) | 25 (30.1) | 28 (35.9) |
| Impaired vision | 48 (29.8) | 20 (24.1) | 28 (35.9) |
| Back pain | 47 (29.2) | 25 (30.1) | 22 (28.2) |
| Osteoarthritis, degenerative arthritis | 29 (18.0) | 13 (15.7) | 16 (20.5) |
| Depression | 25 (15.5) | 12 (14.5) | 13 (16.7) |
| Allergies | 24 (14.9) | 11 (13.3) | 13 (16.7) |
| Impaired hearing | 23 (14.3) | 12 (14.5) | 11 (14.1) |
| Thyroid disorders | 17 (10.6) | 7 (8.4) | 10 (12.8) |
| Lung disease | 15 (9.3) | 7 (8.4) | 8 (10.3) |
| Rheumatoid arthritis | 14 (8.7) | 7 (8.4) | 7 (9.0) |
| Diabetes | 11 (6.8) | 4 (4.8) | 7 (9.0) |
| Cataract surgery | 11 (6.8) | 7 (8.4) | 4 (5.1) |
| Gut disease other than u lcer or stomach disease | 10 (6.2) | 4 (4.8) | 6 (7.7) |
| Ulcer or stomach disease | 9 (5.6) | 5 (6.0) | 4 (5.1) |
| Chronic skin disorders | 9 (5.6) | 6 (7.2) | 3 (3.9) |
| Anemia or other blood disease | 9 (5.6) | 3 (3.6) | 6 (7.7) |
| Congestive heart failure | 8 (5.0) | 6 (7.2) | 2 (2.6) |
| Chronic genitourinary diseases | 8 (5.0) | 3 (3.6) | 5 (6.4) |
| Impaired extremities | 7 (4.4) | 3 (3.6) | 4 (5.1) |
| Coronary heart disease | 6 (3.7) | 3 (3.6) | 3 (3.9) |
| Liver disease | 4 (2.5) | 2 (2.4) | 2 (2.6) |
| Hormonal disorders | 4 (2.5) | 0 (0) | 4 (5.1) |
| Kidney disease | 1 (0.6) | 1 (1.2) | 0 (0) |
| Variable . | Total (N = 161) n (%) . | ATRA-ATO (N = 83) n (%) . | ATRA chemotherapy (N = 78) n (%) . |
|---|---|---|---|
| Hypertension | 53 (32.9) | 25 (30.1) | 28 (35.9) |
| Impaired vision | 48 (29.8) | 20 (24.1) | 28 (35.9) |
| Back pain | 47 (29.2) | 25 (30.1) | 22 (28.2) |
| Osteoarthritis, degenerative arthritis | 29 (18.0) | 13 (15.7) | 16 (20.5) |
| Depression | 25 (15.5) | 12 (14.5) | 13 (16.7) |
| Allergies | 24 (14.9) | 11 (13.3) | 13 (16.7) |
| Impaired hearing | 23 (14.3) | 12 (14.5) | 11 (14.1) |
| Thyroid disorders | 17 (10.6) | 7 (8.4) | 10 (12.8) |
| Lung disease | 15 (9.3) | 7 (8.4) | 8 (10.3) |
| Rheumatoid arthritis | 14 (8.7) | 7 (8.4) | 7 (9.0) |
| Diabetes | 11 (6.8) | 4 (4.8) | 7 (9.0) |
| Cataract surgery | 11 (6.8) | 7 (8.4) | 4 (5.1) |
| Gut disease other than u lcer or stomach disease | 10 (6.2) | 4 (4.8) | 6 (7.7) |
| Ulcer or stomach disease | 9 (5.6) | 5 (6.0) | 4 (5.1) |
| Chronic skin disorders | 9 (5.6) | 6 (7.2) | 3 (3.9) |
| Anemia or other blood disease | 9 (5.6) | 3 (3.6) | 6 (7.7) |
| Congestive heart failure | 8 (5.0) | 6 (7.2) | 2 (2.6) |
| Chronic genitourinary diseases | 8 (5.0) | 3 (3.6) | 5 (6.4) |
| Impaired extremities | 7 (4.4) | 3 (3.6) | 4 (5.1) |
| Coronary heart disease | 6 (3.7) | 3 (3.6) | 3 (3.9) |
| Liver disease | 4 (2.5) | 2 (2.4) | 2 (2.6) |
| Hormonal disorders | 4 (2.5) | 0 (0) | 4 (5.1) |
| Kidney disease | 1 (0.6) | 1 (1.2) | 0 (0) |