Definition of GVL and noGVL
| GVL . | noGVL . |
|---|---|
| Relative decrease of host chimerism by ≥50% (compared with previous time point) or absolute decrease by ≥1.00% or Stable* host chimerism after previous GVL and/or Conversion of MRD from positive to negative or MRD level decrease by ≥10-fold and no cytologic or extramedullary relapse/progressive disease | Stable*/increased host chimerism (compared with previous time point) and/or MRD persistence or MRD level decrease by <10-fold and/or molecular, cytologic, or extramedullary relapse/progressive disease |
| GVL . | noGVL . |
|---|---|
| Relative decrease of host chimerism by ≥50% (compared with previous time point) or absolute decrease by ≥1.00% or Stable* host chimerism after previous GVL and/or Conversion of MRD from positive to negative or MRD level decrease by ≥10-fold and no cytologic or extramedullary relapse/progressive disease | Stable*/increased host chimerism (compared with previous time point) and/or MRD persistence or MRD level decrease by <10-fold and/or molecular, cytologic, or extramedullary relapse/progressive disease |
Stable host chimerism was defined as <50% decrease or increase of host chimerism compared with previous time point.