Table 1. Demographic and clinical... | American Society of Hematology

Table 1.

Demographic and clinical features of the 196 participants in the SIT Trial

Characteristic	Transfusion (n = 90)	Standard care (n = 106)	P
Age, median [IQR], y	10.0 [3.7]	9.8 [4.4]	.925*
Male sex, n (%)	33 (36.7)	52 (49.1)	.081^#
No. of hospitalizations	144	269	<.001†
Length of stay, median [IQR], d	2.0 [2.0]	3.0 [3.0]	<.001*
Total length of stay (hospital days)	358	912	<.001†
Cerebral infarct incidence (per 100 patient-years)	2.0	5.6	.02‡
Hospitalizations for adverse events†
Vaso-occlusive pain	54	151	<.001
ACS	5	34	<.001
Fever without source	12	11	.570
Fever with source	4	7	.538
Sepsis	2	0	.213
Osteomyelitis	0	2	.290
Infection	9	8	.584
Acute anemia	1	1	.923
Splenic sequestration	3	1	.303
Aplastic crisis	0	1	.538
Priapism	1	1	.923
Surgery (specialty type)	16	18	.915
Transfusion reaction, shock, oliguria, hemoglobinuria	1	0	.462
Asthma	3	5	.651
Headache	4	7	.538
Other event	29	22	.130

Characteristic	Transfusion (n = 90)	Standard care (n = 106)	P
Age, median [IQR], y	10.0 [3.7]	9.8 [4.4]	.925*
Male sex, n (%)	33 (36.7)	52 (49.1)	.081^#
No. of hospitalizations	144	269	<.001†
Length of stay, median [IQR], d	2.0 [2.0]	3.0 [3.0]	<.001*
Total length of stay (hospital days)	358	912	<.001†
Cerebral infarct incidence (per 100 patient-years)	2.0	5.6	.02‡
Hospitalizations for adverse events†
Vaso-occlusive pain	54	151	<.001
ACS	5	34	<.001
Fever without source	12	11	.570
Fever with source	4	7	.538
Sepsis	2	0	.213
Osteomyelitis	0	2	.290
Infection	9	8	.584
Acute anemia	1	1	.923
Splenic sequestration	3	1	.303
Aplastic crisis	0	1	.538
Priapism	1	1	.923
Surgery (specialty type)	16	18	.915
Transfusion reaction, shock, oliguria, hemoglobinuria	1	0	.462
Asthma	3	5	.651
Headache	4	7	.538
Other event	29	22	.130

IQR, interquartile range.

Mann-Whitney U test.

χ² test.

Mid-P exact test.

Permutation test.