Hematologic and spleen parameters over time for MF-CP patients (n = 9)
| . | Baseline . | 30 days since last dose . | Difference . | P . | |||
|---|---|---|---|---|---|---|---|
| Median . | Range . | Median . | Range . | Median . | Range . | ||
| WBC, ×103/µL | 10.4 | 3.6-19.9 | 7.65 | 0.8-37 | −0.3 | –6.2-16.6 | .3223 |
| Hemoglobin, g/dL | 9.5 | 6.7-12.1 | 8.7 | 5.8-12.6 | −0.7 | –6.3-2 | .6074 |
| Platelets, ×103/µL | 63.0 | 31.0-901.0 | 107.0 | 20.0-1262.0 | 9.0 | –11.0-361.0 | .3613 |
| Neutrophils, % | 55.0 | 25.0-79.4 | 55.0 | 5.0-90.0 | 1.0 | –23.0-12.0 | .5391 |
| ANC, ×103/µL | 6.6 | 2.1-9.7 | 6.0 | 0.04-16.1 | 0.3 | –3.7-8.5 | .7695 |
| Lymphocytes, % | 12.0 | 7.0-21.0 | 15.0 | 4.0-63.0 | −1.0 | –8.0-52.0 | 1.0000 |
| Blasts, % | 1.0 | 0-7.0 | 1.0 | 0-4.0 | 0 | –5.0-3.0 | .8438 |
| Spleen length, cm | 12.0 | 5.0-20.0 | 13.0 | 1.0-20.0 | 0 | 0-7.0 | .2500 |
| . | Baseline . | 30 days since last dose . | Difference . | P . | |||
|---|---|---|---|---|---|---|---|
| Median . | Range . | Median . | Range . | Median . | Range . | ||
| WBC, ×103/µL | 10.4 | 3.6-19.9 | 7.65 | 0.8-37 | −0.3 | –6.2-16.6 | .3223 |
| Hemoglobin, g/dL | 9.5 | 6.7-12.1 | 8.7 | 5.8-12.6 | −0.7 | –6.3-2 | .6074 |
| Platelets, ×103/µL | 63.0 | 31.0-901.0 | 107.0 | 20.0-1262.0 | 9.0 | –11.0-361.0 | .3613 |
| Neutrophils, % | 55.0 | 25.0-79.4 | 55.0 | 5.0-90.0 | 1.0 | –23.0-12.0 | .5391 |
| ANC, ×103/µL | 6.6 | 2.1-9.7 | 6.0 | 0.04-16.1 | 0.3 | –3.7-8.5 | .7695 |
| Lymphocytes, % | 12.0 | 7.0-21.0 | 15.0 | 4.0-63.0 | −1.0 | –8.0-52.0 | 1.0000 |
| Blasts, % | 1.0 | 0-7.0 | 1.0 | 0-4.0 | 0 | –5.0-3.0 | .8438 |
| Spleen length, cm | 12.0 | 5.0-20.0 | 13.0 | 1.0-20.0 | 0 | 0-7.0 | .2500 |
ANC, absolute neutrophil count; WBC, white blood cell.