Table 4.

Sensitivity analysis: complete response treatment effect of tisagenlecleucel vs blinatumomab

MethodOR95% CIP
Unadjusted OR    
 Univariate logistic regression 3.39 1.78-6.45 .0002 
Marginal OR (adjusted)    
 Logistic regression with sIPTW 3.46 1.82-6.59 .0002 
 Logistic regression with trimmed sIPTW 3.68 1.93-7.04 <.0001 
Conditional OR (adjusted)    
 Logistic regression stratified by quintiles of propensity score 3.08 1.56-6.09 .0012 
 Logistic regression adjusting for prognostic factors 3.83 1.88-7.79 .0002 
 Logistic regression adjusting for prognostic factors and propensity score 3.84 1.89-7.83 .0002 
MethodOR95% CIP
Unadjusted OR    
 Univariate logistic regression 3.39 1.78-6.45 .0002 
Marginal OR (adjusted)    
 Logistic regression with sIPTW 3.46 1.82-6.59 .0002 
 Logistic regression with trimmed sIPTW 3.68 1.93-7.04 <.0001 
Conditional OR (adjusted)    
 Logistic regression stratified by quintiles of propensity score 3.08 1.56-6.09 .0012 
 Logistic regression adjusting for prognostic factors 3.83 1.88-7.79 .0002 
 Logistic regression adjusting for prognostic factors and propensity score 3.84 1.89-7.83 .0002 

OR is the odds ratio of tisagenlecleucel vs blinatumomab. An OR >1 indicates that tisagenlecleucel is associated with a higher odds of response than blinatumomab.

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