Numbers of significantly dysregulated genes for all the patient groups show a skewing toward upregulation of differentially expressed genes
| Analysis group . | Total gene count* . | FDR < 0.05 . | ||
|---|---|---|---|---|
| No. . | % . | No. . | % . | |
| FANC v controls | ||||
| All | 16 853 | 875 | 5.19 | |
| Upregulated | 7 993 | 47 | 710 | 81 |
| Downregulated | 8 860 | 53 | 165 | 19 |
| SBDS v controls | ||||
| All | 14 795 | 452 | 3.06 | |
| Upregulated | 7 296 | 49 | 334 | 74 |
| Downregulated | 7 499 | 51 | 118 | 26 |
| DKC1 v controls | ||||
| All | 16 324 | 424 | 2.60 | |
| Upregulated | 7 888 | 48 | 259 | 61 |
| Downregulated | 8 435 | 52 | 165 | 39 |
| TRI v controls | ||||
| All | 16 174 | 1023 | 6.32 | |
| Upregulated | 8 008 | 50 | 820 | 80 |
| Downregulated | 8 166 | 50 | 203 | 20 |
| SNGL v controls | ||||
| All | 14 922 | 640 | 4.29 | |
| Upregulated | 7 176 | 48 | 538 | 84 |
| Downregulated | 7 746 | 52 | 102 | 16 |
| Analysis group . | Total gene count* . | FDR < 0.05 . | ||
|---|---|---|---|---|
| No. . | % . | No. . | % . | |
| FANC v controls | ||||
| All | 16 853 | 875 | 5.19 | |
| Upregulated | 7 993 | 47 | 710 | 81 |
| Downregulated | 8 860 | 53 | 165 | 19 |
| SBDS v controls | ||||
| All | 14 795 | 452 | 3.06 | |
| Upregulated | 7 296 | 49 | 334 | 74 |
| Downregulated | 7 499 | 51 | 118 | 26 |
| DKC1 v controls | ||||
| All | 16 324 | 424 | 2.60 | |
| Upregulated | 7 888 | 48 | 259 | 61 |
| Downregulated | 8 435 | 52 | 165 | 39 |
| TRI v controls | ||||
| All | 16 174 | 1023 | 6.32 | |
| Upregulated | 8 008 | 50 | 820 | 80 |
| Downregulated | 8 166 | 50 | 203 | 20 |
| SNGL v controls | ||||
| All | 14 922 | 640 | 4.29 | |
| Upregulated | 7 176 | 48 | 538 | 84 |
| Downregulated | 7 746 | 52 | 102 | 16 |
All data are reported from DESeq2 analysis of 3 patients against 3 controls.
Only genes with an FDR statistic are included in the analysis.