Suggested factor replacement schedule for older adult persons with hemophilia A or B without inhibitors based on WFH guidelines
| Indication . | Hemophilia A . | Hemophilia B . | ||
|---|---|---|---|---|
| Target peak levels (%) . | Duration . | Target peak levels (%) . | Duration . | |
| Minor surgery | 50-80 | Day of surgery | 50-80 | Day of surgery |
| 30-80 | Days 1-5 | 30-80 | Days 1-5 | |
| Major surgery | 80-100 | Day of surgery | 60-80 | Day of surgery |
| 60-80 | Days 1-3 | 40-60 | Days 1-3 | |
| 40-60 | Days 4-6 | 30-50 | Days 4-6 | |
| 30-50 | Days 7-14 | 20-40 | Days 7-14 | |
| Indication . | Hemophilia A . | Hemophilia B . | ||
|---|---|---|---|---|
| Target peak levels (%) . | Duration . | Target peak levels (%) . | Duration . | |
| Minor surgery | 50-80 | Day of surgery | 50-80 | Day of surgery |
| 30-80 | Days 1-5 | 30-80 | Days 1-5 | |
| Major surgery | 80-100 | Day of surgery | 60-80 | Day of surgery |
| 60-80 | Days 1-3 | 40-60 | Days 1-3 | |
| 40-60 | Days 4-6 | 30-50 | Days 4-6 | |
| 30-50 | Days 7-14 | 20-40 | Days 7-14 | |
Adapted with permission from Srivastava et al.16