Table 3.

Supportive care recommendations for ocular chronic GVHD

Topical and oral therapies 
 Artificial tears, preservative free
 Viscous ointment at bedtime/viscous tears during the day
 Cyclosporine and topical steroid eye drops
 Oral agents such as cevimeline and pilocarpine
 Doxycycline to reduce inflammation 
Surgical 
 Punctal occlusion (temporary using silicone plugs)
 Permanent occlusion using thermal cautery
 Superficial debridement of filamentary keratitis
 Partial tarsorrhaphy 
Eye wear/environmental strategy 
 Occlusive eye wear (moisture chamber goggles)
 Lid care/warm compressors/humidified environment
 Bandage contact lens 
Treatments not widely available 
 Autologous serum eye drops
 Gas-permeable contact lens (scleral lens prosthesis) 
Topical and oral therapies 
 Artificial tears, preservative free
 Viscous ointment at bedtime/viscous tears during the day
 Cyclosporine and topical steroid eye drops
 Oral agents such as cevimeline and pilocarpine
 Doxycycline to reduce inflammation 
Surgical 
 Punctal occlusion (temporary using silicone plugs)
 Permanent occlusion using thermal cautery
 Superficial debridement of filamentary keratitis
 Partial tarsorrhaphy 
Eye wear/environmental strategy 
 Occlusive eye wear (moisture chamber goggles)
 Lid care/warm compressors/humidified environment
 Bandage contact lens 
Treatments not widely available 
 Autologous serum eye drops
 Gas-permeable contact lens (scleral lens prosthesis) 
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