Supportive care recommendations for ocular chronic GVHD
Topical and oral therapies |
Artificial tears, preservative free Viscous ointment at bedtime/viscous tears during the day Cyclosporine and topical steroid eye drops Oral agents such as cevimeline and pilocarpine Doxycycline to reduce inflammation |
Surgical |
Punctal occlusion (temporary using silicone plugs) Permanent occlusion using thermal cautery Superficial debridement of filamentary keratitis Partial tarsorrhaphy |
Eye wear/environmental strategy |
Occlusive eye wear (moisture chamber goggles) Lid care/warm compressors/humidified environment Bandage contact lens |
Treatments not widely available |
Autologous serum eye drops Gas-permeable contact lens (scleral lens prosthesis) |
Topical and oral therapies |
Artificial tears, preservative free Viscous ointment at bedtime/viscous tears during the day Cyclosporine and topical steroid eye drops Oral agents such as cevimeline and pilocarpine Doxycycline to reduce inflammation |
Surgical |
Punctal occlusion (temporary using silicone plugs) Permanent occlusion using thermal cautery Superficial debridement of filamentary keratitis Partial tarsorrhaphy |
Eye wear/environmental strategy |
Occlusive eye wear (moisture chamber goggles) Lid care/warm compressors/humidified environment Bandage contact lens |
Treatments not widely available |
Autologous serum eye drops Gas-permeable contact lens (scleral lens prosthesis) |