Predictors of cardiac toxicity: multivariate analysis
| Covariable . | HR (95% CI) . | P . |
|---|---|---|
| Cardiac risk stratification score 0-1 2 3-4 | 1 2.2 (1.0-4.8) 5.6 (2.6-11.9) | .05 <.001 |
| PTCy | 1.1 (0.6-2.1) | .7 |
| Covariable . | HR (95% CI) . | P . |
|---|---|---|
| Cardiac risk stratification score 0-1 2 3-4 | 1 2.2 (1.0-4.8) 5.6 (2.6-11.9) | .05 <.001 |
| PTCy | 1.1 (0.6-2.1) | .7 |
Proposed Cardiac Risk Stratification Score includes 5 predictors of cardiac toxicity: age >55, HTN, cardiac, arrhythmia, and diabetes. Cardiac, includes coronary artery disease (≥1 vessel coronary artery stenosis requiring medical treatment, stent, or bypass graft), congestive heart failure, myocardial infarction, or ejection fraction ≤50%. Arrhythmia includes atrial fibrillation or flutter, sick sinus syndrome, or ventricular arrhythmia. Score 3-4 vs 2: HR, 2.5 (95% CI 1.2-5.5); P = 0.02.