Grade 3 or higher nonhematologic adverse events within 100 days of transplant
| Adverse event . | Grade 3 . | Grade 4 . | Grade 5 . |
|---|---|---|---|
| Gastrointestinal | |||
| Abdominal pain | 2 (10%) | 0 | 0 |
| Anorexia | 2 (10%) | 0 | 0 |
| Diarrhea | 2 (10%) | 0 | 0 |
| Enterocolitis | 1 (5%) | 0 | 0 |
| Esophageal varices | 1 (5%) | 0 | 0 |
| Gastrointestinal GVHD | 1 (5%) | 0 | 0 |
| Nausea | 1 (5%) | 0 | 0 |
| General disorders | |||
| Angioedema | 1 (5%) | 0 | 0 |
| Facial edema | 2 (10%) | 0 | 0 |
| Fatigue | 3 (15%) | 0 | 0 |
| Ocular GVHD | 1 (5%) | 0 | 0 |
| Periorbital edema | 1 (5%) | 0 | 0 |
| Tongue swelling | 1 (5%) | 0 | 0 |
| Infections and infestations | |||
| Escherichia coli bacteremia | 1 (5%) | 0 | 0 |
| Blood infection | 1 (5%) | 0 | 1 (5%) |
| Neutropenic fever | 5 (25%) | 0 | 0 |
| Wound infection | 1 (5%) | 0 | 0 |
| Investigations | |||
| Acute renal injury | 3 (15%) | 0 | 0 |
| Elevated bilirubin | 1 (5%) | 0 | 0 |
| Urinary retention | 1 (5%) | 0 | 0 |
| Metabolism and nutrition | |||
| Hyperglycemia | 1 (5%) | 0 | 0 |
| Hypophosphatemia | 4 (20%) | 0 | 0 |
| Nervous system disorders | |||
| Dizziness | 1 (5%) | 0 | 0 |
| Extrapyramidal disorder | 0 | 0 | 1 (5%) |
| Respiratory and thoracic disorder | |||
| Adenovirus pneumonia | 0 | 0 | 1 (5%) |
| Acute respiratory distress syndrome | 0 | 2 (10%) | 0 |
| Ascites | 0 | 1 (5%) | 0 |
| Chest wall pain | 1 (5%) | 0 | 0 |
| Dyspnea | 1 (5%) | 0 | 0 |
| Hypoxia | 2 (10%) | 0 | 0 |
| Pneumonitis | 1 (5%) | 0 | 0 |
| Skin | |||
| Rash | 6 (30%) | 0 | |
| Vascular | |||
| Cerebral infarct | 0 | 1 (5%) | 0 |
| Hematoma | 0 | 1 (5%) | 0 |
| Pulmonary embolism | 1 (5%) | 0 | 0 |
| Syncope | 1 (5%) | 0 | 0 |
| Adverse event . | Grade 3 . | Grade 4 . | Grade 5 . |
|---|---|---|---|
| Gastrointestinal | |||
| Abdominal pain | 2 (10%) | 0 | 0 |
| Anorexia | 2 (10%) | 0 | 0 |
| Diarrhea | 2 (10%) | 0 | 0 |
| Enterocolitis | 1 (5%) | 0 | 0 |
| Esophageal varices | 1 (5%) | 0 | 0 |
| Gastrointestinal GVHD | 1 (5%) | 0 | 0 |
| Nausea | 1 (5%) | 0 | 0 |
| General disorders | |||
| Angioedema | 1 (5%) | 0 | 0 |
| Facial edema | 2 (10%) | 0 | 0 |
| Fatigue | 3 (15%) | 0 | 0 |
| Ocular GVHD | 1 (5%) | 0 | 0 |
| Periorbital edema | 1 (5%) | 0 | 0 |
| Tongue swelling | 1 (5%) | 0 | 0 |
| Infections and infestations | |||
| Escherichia coli bacteremia | 1 (5%) | 0 | 0 |
| Blood infection | 1 (5%) | 0 | 1 (5%) |
| Neutropenic fever | 5 (25%) | 0 | 0 |
| Wound infection | 1 (5%) | 0 | 0 |
| Investigations | |||
| Acute renal injury | 3 (15%) | 0 | 0 |
| Elevated bilirubin | 1 (5%) | 0 | 0 |
| Urinary retention | 1 (5%) | 0 | 0 |
| Metabolism and nutrition | |||
| Hyperglycemia | 1 (5%) | 0 | 0 |
| Hypophosphatemia | 4 (20%) | 0 | 0 |
| Nervous system disorders | |||
| Dizziness | 1 (5%) | 0 | 0 |
| Extrapyramidal disorder | 0 | 0 | 1 (5%) |
| Respiratory and thoracic disorder | |||
| Adenovirus pneumonia | 0 | 0 | 1 (5%) |
| Acute respiratory distress syndrome | 0 | 2 (10%) | 0 |
| Ascites | 0 | 1 (5%) | 0 |
| Chest wall pain | 1 (5%) | 0 | 0 |
| Dyspnea | 1 (5%) | 0 | 0 |
| Hypoxia | 2 (10%) | 0 | 0 |
| Pneumonitis | 1 (5%) | 0 | 0 |
| Skin | |||
| Rash | 6 (30%) | 0 | |
| Vascular | |||
| Cerebral infarct | 0 | 1 (5%) | 0 |
| Hematoma | 0 | 1 (5%) | 0 |
| Pulmonary embolism | 1 (5%) | 0 | 0 |
| Syncope | 1 (5%) | 0 | 0 |