Broad race categories for leader peptides observed in cohort 1
| Deduced leader peptide . | . | Hispanic or Latino . | Asian or Pacific Islander . | Black or African American . | American Indian or Alaskan Native . | Multirace . | Unknown . | Total (% of cohort total) . |
|---|---|---|---|---|---|---|---|---|
| White . | Percentage by leader peptide’s total, horizontally (%); percentage by broad race’s total, vertically (%) . | |||||||
| VMAPRTVLL* | 64.5; 34.2 | 15.9; 30.3 | 3.6; 14.8 | 3.8; 25.5 | 0.3; 27.7 | 11.1; 29.4 | 0.9; 33.3 | 683 153 (31.1) |
| VTAPRTVLL† | 47.8; | 19.6; | 11.4; | 7.2; | 0.4; | 12.9; | 0.6; | 670 904 (30.5) |
| 24.9 | 36.7 | 46.5 | 47.7 | 34.4 | 33.5 | 23.4 | ||
| VTAPRTLLL‡ | 63.2; | 15.2; | 7.0; | 2.3; | 0.4; | 11.1; | 0.9; | 542 311 (24.7) |
| 26.6 | 23.0 | 22.9 | 12.0 | 26.8 | 23.3 | 28.0 | ||
| VTAPRTVLL† | 61.9; | 12.7; | 6.7; | 5.8; | 0.3; | 11.8; | 0.9; | 242 366 (11.0) |
| 11.6 | 8.6 | 9.8 | 13.8 | 8.9 | 11.0 | 12.8 | ||
| VTAPRTLLL‡ | 59.5; | 8.8; | 16.9; | 1.6; | 0.3; | 12.1; | 0.7; | 57 747 (2.6) |
| 2.7 | 1.4 | 5.9 | 0.9 | 2.2 | 2.7 | 2.4 | ||
| VTEPRTLLL | 77.6 | 10.3 | — | 0.9 | — | 11.2 | — | 107 |
| VMAPRTVLL* | 92.0 | 4.0 | — | — | — | 4.0 | — | 25 |
| VMAPRTVLL* | 9.5 | — | 71.4 | — | 4.8 | 14.3 | — | 21 |
| VTAPRTVLL† | 6.3 | 31.3 | — | 56.3 | — | 6.3 | — | 16 |
| VTAPRTLLL‡ | 10.0 | 50.0 | 40.0 | — | — | — | — | 10 |
| VTAPRTLFL | 100.0 | — | — | — | — | — | — | 7 |
| VTASRTLLL | — | 50.0 | — | 16.7 | — | 33.3 | — | 6 |
| VMAPRTLLL | 80.0 | — | 20.0 | — | — | — | — | 5 |
| VTASRTVLL | 75.0 | — | — | — | — | 25.0 | — | 4 |
| VRAPRTLLL | 33.3 | — | 66.7 | — | — | — | — | 3 |
| VTAPRTILL | 100.0 | — | — | — | — | — | — | 3 |
| VTAPRNLLL | 100.0 | — | — | — | — | — | — | 3 |
| VMAPRTVLL* | 100.0 | — | — | — | — | — | — | 3 |
| VTAPRTVLL† | — | — | 66.7 | — | — | 33.3 | — | 3 |
| VTAPQTVLL | 33.3 | — | — | — | — | 66.7 | — | 3 |
| VTATRTLLL | 100.0 | — | — | — | — | — | — | 2 |
| VTALRTVLL | — | 100.0 | — | — | — | — | — | 1 |
| VTAPRTLVL | 100.0 | — | — | — | — | — | — | 1 |
| ITAPRTVLL | — | — | — | — | — | — | 100.0 | 1 |
| VMEPRTVLL | 100.0 | — | — | — | — | — | — | 1 |
| VTAP*TLLL | 100.0 | — | — | — | — | — | — | 1 |
| VTAPRTLLL‡ | — | 100.0 | — | — | — | — | — | 1 |
| VTAPRTFLL | 100.0 | — | — | — | — | — | — | 1 |
| VMATRTVLL | — | 100.0 | — | — | — | — | — | 1 |
| VMAPGTVLL | — | — | 100.0 | — | — | — | — | 1 |
| VTAPRTVLQ | 100.0 | — | — | — | — | — | — | 1 |
| VMAPRSVLL | — | — | — | — | — | 100.0 | — | 1 |
| VVAPRTVLL | 100.0 | — | — | — | — | — | — | 1 |
| VMVPRTVLL | 100.0 | — | — | — | — | — | — | 1 |
| VMAPRTVLV | — | — | 100.0 | — | — | — | — | 1 |
| Total (% by cohort total) | 1 288 740 (58.7%) | 358 322 (16.3%) | 164 740 (7.5%) | 101 512 (4.6%) | 7104 (0.3%) | 258 404 (11.8%) | 17 592 (0.8%) | 2 196 716 |
| Deduced leader peptide . | . | Hispanic or Latino . | Asian or Pacific Islander . | Black or African American . | American Indian or Alaskan Native . | Multirace . | Unknown . | Total (% of cohort total) . |
|---|---|---|---|---|---|---|---|---|
| White . | Percentage by leader peptide’s total, horizontally (%); percentage by broad race’s total, vertically (%) . | |||||||
| VMAPRTVLL* | 64.5; 34.2 | 15.9; 30.3 | 3.6; 14.8 | 3.8; 25.5 | 0.3; 27.7 | 11.1; 29.4 | 0.9; 33.3 | 683 153 (31.1) |
| VTAPRTVLL† | 47.8; | 19.6; | 11.4; | 7.2; | 0.4; | 12.9; | 0.6; | 670 904 (30.5) |
| 24.9 | 36.7 | 46.5 | 47.7 | 34.4 | 33.5 | 23.4 | ||
| VTAPRTLLL‡ | 63.2; | 15.2; | 7.0; | 2.3; | 0.4; | 11.1; | 0.9; | 542 311 (24.7) |
| 26.6 | 23.0 | 22.9 | 12.0 | 26.8 | 23.3 | 28.0 | ||
| VTAPRTVLL† | 61.9; | 12.7; | 6.7; | 5.8; | 0.3; | 11.8; | 0.9; | 242 366 (11.0) |
| 11.6 | 8.6 | 9.8 | 13.8 | 8.9 | 11.0 | 12.8 | ||
| VTAPRTLLL‡ | 59.5; | 8.8; | 16.9; | 1.6; | 0.3; | 12.1; | 0.7; | 57 747 (2.6) |
| 2.7 | 1.4 | 5.9 | 0.9 | 2.2 | 2.7 | 2.4 | ||
| VTEPRTLLL | 77.6 | 10.3 | — | 0.9 | — | 11.2 | — | 107 |
| VMAPRTVLL* | 92.0 | 4.0 | — | — | — | 4.0 | — | 25 |
| VMAPRTVLL* | 9.5 | — | 71.4 | — | 4.8 | 14.3 | — | 21 |
| VTAPRTVLL† | 6.3 | 31.3 | — | 56.3 | — | 6.3 | — | 16 |
| VTAPRTLLL‡ | 10.0 | 50.0 | 40.0 | — | — | — | — | 10 |
| VTAPRTLFL | 100.0 | — | — | — | — | — | — | 7 |
| VTASRTLLL | — | 50.0 | — | 16.7 | — | 33.3 | — | 6 |
| VMAPRTLLL | 80.0 | — | 20.0 | — | — | — | — | 5 |
| VTASRTVLL | 75.0 | — | — | — | — | 25.0 | — | 4 |
| VRAPRTLLL | 33.3 | — | 66.7 | — | — | — | — | 3 |
| VTAPRTILL | 100.0 | — | — | — | — | — | — | 3 |
| VTAPRNLLL | 100.0 | — | — | — | — | — | — | 3 |
| VMAPRTVLL* | 100.0 | — | — | — | — | — | — | 3 |
| VTAPRTVLL† | — | — | 66.7 | — | — | 33.3 | — | 3 |
| VTAPQTVLL | 33.3 | — | — | — | — | 66.7 | — | 3 |
| VTATRTLLL | 100.0 | — | — | — | — | — | — | 2 |
| VTALRTVLL | — | 100.0 | — | — | — | — | — | 1 |
| VTAPRTLVL | 100.0 | — | — | — | — | — | — | 1 |
| ITAPRTVLL | — | — | — | — | — | — | 100.0 | 1 |
| VMEPRTVLL | 100.0 | — | — | — | — | — | — | 1 |
| VTAP*TLLL | 100.0 | — | — | — | — | — | — | 1 |
| VTAPRTLLL‡ | — | 100.0 | — | — | — | — | — | 1 |
| VTAPRTFLL | 100.0 | — | — | — | — | — | — | 1 |
| VMATRTVLL | — | 100.0 | — | — | — | — | — | 1 |
| VMAPGTVLL | — | — | 100.0 | — | — | — | — | 1 |
| VTAPRTVLQ | 100.0 | — | — | — | — | — | — | 1 |
| VMAPRSVLL | — | — | — | — | — | 100.0 | — | 1 |
| VVAPRTVLL | 100.0 | — | — | — | — | — | — | 1 |
| VMVPRTVLL | 100.0 | — | — | — | — | — | — | 1 |
| VMAPRTVLV | — | — | 100.0 | — | — | — | — | 1 |
| Total (% by cohort total) | 1 288 740 (58.7%) | 358 322 (16.3%) | 164 740 (7.5%) | 101 512 (4.6%) | 7104 (0.3%) | 258 404 (11.8%) | 17 592 (0.8%) | 2 196 716 |
The deduced leader peptides from Table 1 are related to the corresponding donor’s broad race. The first percentages are based on the leader peptide’s total (horizontal). The top 5 peptides have percentages based on the broad race’s total (vertical) listed second. Deduced leader peptides with multiple unique nucleotide sequences are annotated with footnotes. The cohort total is 2 196 716.
These deduced leader peptides have four unique exon 1 sequences each in cohort 1.