EBV-associated lymphoproliferative diagnoses
| Classification . | Diagnosis . |
|---|---|
| Reactive lymphoid proliferation | HLH CAEBV, B cell, and T/NK cell Hydroa vacciniforme–like lymphoproliferative disorder EBV+ mucocutaneous ulcer Severe mosquito bite allergy |
| B-cell malignancies | Hodgkin Lymphoma Diffuse large B-cell lymphoma Burkitt lymphoma Plasma cell neoplasms Lymphomatoid granulomatosis Plasmablastic lymphoma |
| NK- and T-cell malignancies | Systemic EBV+ T-cell lymphoma of childhood Aggressive NK-cell leukemia Angioimmunoblastic T-cell lymphoma* Follicular T-cell lymphoma* Peripheral T-cell lymphomas Extranodal NK/T-cell lymphoma, nasal type EBV+ nodal T- and NK-cell lymphoma Peripheral T-cell lymphoma, NOS |
| Immunodeficiency related | Posttransplantation lymphoproliferative disorder HIV related Lymphoproliferative disease associated with primary immune deficiencies |
| Classification . | Diagnosis . |
|---|---|
| Reactive lymphoid proliferation | HLH CAEBV, B cell, and T/NK cell Hydroa vacciniforme–like lymphoproliferative disorder EBV+ mucocutaneous ulcer Severe mosquito bite allergy |
| B-cell malignancies | Hodgkin Lymphoma Diffuse large B-cell lymphoma Burkitt lymphoma Plasma cell neoplasms Lymphomatoid granulomatosis Plasmablastic lymphoma |
| NK- and T-cell malignancies | Systemic EBV+ T-cell lymphoma of childhood Aggressive NK-cell leukemia Angioimmunoblastic T-cell lymphoma* Follicular T-cell lymphoma* Peripheral T-cell lymphomas Extranodal NK/T-cell lymphoma, nasal type EBV+ nodal T- and NK-cell lymphoma Peripheral T-cell lymphoma, NOS |
| Immunodeficiency related | Posttransplantation lymphoproliferative disorder HIV related Lymphoproliferative disease associated with primary immune deficiencies |
Shown are diagnoses with proliferative or malignant cells that can demonstrate EBV positivity.
NOS, not otherwise specified.
Angioimmunoblastic T-cell lymphoma and follicular T-cell lymphoma have a follicular T-cell phenotype, but EBV+ B-cell blasts may be present.