Table 4.

Consensus criteria for relapse definition in pediatric ALL: BM relapse (MRD unavailable)

BM 1BM 2*
CytomorphologyOthersCytomorphology
M3 Not necessary to define relapse Not necessary to define relapse 
M2 One other test with ≥1% blasts Not necessary to define relapse 
M2 None M2 
M1 Two other tests with ≥1% blasts Not necessary to define relapse 
BM 1BM 2*
CytomorphologyOthersCytomorphology
M3 Not necessary to define relapse Not necessary to define relapse 
M2 One other test with ≥1% blasts Not necessary to define relapse 
M2 None M2 
M1 Two other tests with ≥1% blasts Not necessary to define relapse 
*

Second bone marrow evaluation ≥1 wk later.

FISH/karyotype/PCR demonstrating leukemia-specific marker.

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