Table 1.

Multivariable analysis of response by patient characteristics significant in univariable analysis

CharacteristicOdds ratio95% CIP
Cumulative fludarabine AUC, mg × h/L 0.81 0.56-1.21 .26 
Race*   .019 
 Black/Hispanic Ref   
 White 5.28 1.37-25.7  
Preinfusion disease burden   <.001 
 None or low Ref   
 High 0.06 0.00-0.32  
Prior CD19-directed therapy   .007 
 No Ref   
 Yes 0.16 0.04-0.60  
CharacteristicOdds ratio95% CIP
Cumulative fludarabine AUC, mg × h/L 0.81 0.56-1.21 .26 
Race*   .019 
 Black/Hispanic Ref   
 White 5.28 1.37-25.7  
Preinfusion disease burden   <.001 
 None or low Ref   
 High 0.06 0.00-0.32  
Prior CD19-directed therapy   .007 
 No Ref   
 Yes 0.16 0.04-0.60  

Ref, reference.

*

No events were observed in the other race groups.

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