Table 1.

Genes identified as misspliced in Srsf2/SRSF2 mutant cells in at least 10 of 16 datasets

GeneDescriptionNo. of datasets (human/murine)
ATF2 Activating transcription factor 2 13 (7H/6M) 
MTMR14 Myotubularin related protein 14 13 (9H/4M) 
HNRNPA2B1 Heterogenous nuclear ribonucleoprotein A2/B1 11 (5H/6M) 
SEC24B SEC24 family member B 11 (6H/5M) 
AGTPBP1 ATP/GTP binding protein 1 10 (5H/5M) 
PRPSAP2 Phosphoribosyl pyrophosphate synthetase-associated protein 2 10 (6H/4M) 
EHMT2 Euchromatic histone-lysine N-methyltransferase 2 10 (5H/5M) 
STRADA STE20-related kinase adaptor α 10 (5H/5M) 
TIA1 TIA1 cytotoxic granule-associated RNA binding protein 10 (5H/5M) 
MTF2 Metal response element binding transcription factor 2 10 (5H/5M) 
RSRC2 Arginine/serine-rich coiled-coil 2 10 (7H/3M) 
CEP57 Centrosomal protein 57kDa 10 (8H/2M) 
FIP1L1 Factor interacting with PAPOLA and CPSF1 10 (7H/3M) 
FYN FYN proto-oncogene, Src family tyrosine kinase 10 (6H/4M) 
ABI1 Abl-interactor 1 10 (6H/4M) 
HUWE1 HECT, UBA, and WWE domain containing 1, E3 ubiquitin protein ligase 10 (5H/5M) 
TPD52L2 Tumor protein D52-like 2 10 (8H/2M) 
ZMYND8 Zinc finger, MYND-type containing 8 10 (7H/3M) 
NSD1 Nuclear receptor binding SET domain protein 1 10 (5H/5M) 
GeneDescriptionNo. of datasets (human/murine)
ATF2 Activating transcription factor 2 13 (7H/6M) 
MTMR14 Myotubularin related protein 14 13 (9H/4M) 
HNRNPA2B1 Heterogenous nuclear ribonucleoprotein A2/B1 11 (5H/6M) 
SEC24B SEC24 family member B 11 (6H/5M) 
AGTPBP1 ATP/GTP binding protein 1 10 (5H/5M) 
PRPSAP2 Phosphoribosyl pyrophosphate synthetase-associated protein 2 10 (6H/4M) 
EHMT2 Euchromatic histone-lysine N-methyltransferase 2 10 (5H/5M) 
STRADA STE20-related kinase adaptor α 10 (5H/5M) 
TIA1 TIA1 cytotoxic granule-associated RNA binding protein 10 (5H/5M) 
MTF2 Metal response element binding transcription factor 2 10 (5H/5M) 
RSRC2 Arginine/serine-rich coiled-coil 2 10 (7H/3M) 
CEP57 Centrosomal protein 57kDa 10 (8H/2M) 
FIP1L1 Factor interacting with PAPOLA and CPSF1 10 (7H/3M) 
FYN FYN proto-oncogene, Src family tyrosine kinase 10 (6H/4M) 
ABI1 Abl-interactor 1 10 (6H/4M) 
HUWE1 HECT, UBA, and WWE domain containing 1, E3 ubiquitin protein ligase 10 (5H/5M) 
TPD52L2 Tumor protein D52-like 2 10 (8H/2M) 
ZMYND8 Zinc finger, MYND-type containing 8 10 (7H/3M) 
NSD1 Nuclear receptor binding SET domain protein 1 10 (5H/5M) 

Genes are ranked by the number of datasets the transcript was identified in. The number of human (H) or murine (M) datasets is indicated in parentheses.

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