RR or OR (95% CI) of low income, part-time employment, or unemployment associated with impairment on neurocognitive, psychosocial, and quality of life measures
| Psychosocial and neurocognitive domains . | College graduate and lower (vs college graduate) RR (95% CI) . | Dependent living (vs independent) RR (95% CI) . | Income less than $20 000 (vs $20 000 or higher)* RR (95% CI) . | Part-time employment (vs fully employed)† OR (95% CI) . | Unemployed (vs fully employed)† OR (95% CI) . |
|---|---|---|---|---|---|
| Neurocognitive factors‡ | |||||
| Task efficiency | 0.97 (0.78-1.21) | 1.58 (0.89-2.79) | 1.42 (1.08-1.87) | 1.76 (0.87-3.54) | 3.41 (1.91-6.07) |
| Emotional regulation | 1.20 (1.01-1.43) | 0.90 (0.57-1.43) | 1.16 (0.92-1.46) | 1.30 (0.77-2.18) | 1.27 (0.74-2.17) |
| Organization | 0.82 (0.67-1.02) | 1.48 (0.95-2.29) | 1.21 (0.94-1.54) | 1.27 (0.70-2.31) | 0.77 (0.42-1.39) |
| Memory | 1.29 (1.04-1.59) | 0.86 (0.46-1.62) | 1.02 (0.77-1.35) | 0.61 (0.28-1.35) | 1.89 (1.02-3.48) |
| Psychosocial factors‡ | |||||
| Anxiety | 0.73 (0.57-0.95) | 0.68 (0.35-1.31) | 0.71 (0.51-0.99) | 0.88 (0.35-2.22) | 0.37 (0.17-0.81) |
| Depression | 1.24 (1.01-1.53) | 1.79 (1.02-3.15) | 1.30 (0.98-1.74) | 0.68 (0.29-1.56) | 1.87 (1.01-3.46) |
| Quality of life measures | |||||
| General health | 1.10 (0.89-1.35) | 1.29 (0.84-1.97) | 1.10 (0.85-1.41) | 1.16 (0.74-1.83) | 1.49 (0.91-2.46) |
| Physical function | 1.12 (0.84-1.48) | 1.12 (0.62-2.04) | 1.42 (1.04-1.94) | 1.35 (0.70-2.63) | 2.24 (1.30-3.85) |
| Physical role limitation | 1.10 (0.84-1.44) | 1.13 (0.65-1.97) | 1.96 (1.44-2.66) | 1.71 (0.92-3.18) | 4.06 (2.36-7.00) |
| Pain | 1.27 (1.00-1.62) | 0.97 (0.57-1.63) | 1.04 (0.78-1.38) | 1.03 (0.58-1.83) | 0.97 (0.57-1.65) |
| Emotional role limitation | 0.99 (0.77-1.26) | 1.06 (0.64-1.73) | 0.93 (0.70-1.24) | 0.91 (0.51-1.62) | 1.16 (0.70-1.94) |
| Vitality | 1.02 (0.81-1.28) | 1.35 (0.86-2.13) | 0.99 (0.75-1.29) | 0.76 (0.45-1.28) | 1.26 (0.76-2.08) |
| Social functioning | 1.15 (0.88-1.51) | 1.03 (0.59-1.79) | 0.94 (0.68-1.28) | 0.77 (0.40-1.51) | 1.67 (0.97-2.88) |
| Mental health | 1.07 (0.83-1.38) | 1.26 (0.76-2.08) | 1.15 (0.85-1.54) | 1.17 (0.64-2.14) | 1.4 (0.83-2.36) |
| Psychosocial and neurocognitive domains . | College graduate and lower (vs college graduate) RR (95% CI) . | Dependent living (vs independent) RR (95% CI) . | Income less than $20 000 (vs $20 000 or higher)* RR (95% CI) . | Part-time employment (vs fully employed)† OR (95% CI) . | Unemployed (vs fully employed)† OR (95% CI) . |
|---|---|---|---|---|---|
| Neurocognitive factors‡ | |||||
| Task efficiency | 0.97 (0.78-1.21) | 1.58 (0.89-2.79) | 1.42 (1.08-1.87) | 1.76 (0.87-3.54) | 3.41 (1.91-6.07) |
| Emotional regulation | 1.20 (1.01-1.43) | 0.90 (0.57-1.43) | 1.16 (0.92-1.46) | 1.30 (0.77-2.18) | 1.27 (0.74-2.17) |
| Organization | 0.82 (0.67-1.02) | 1.48 (0.95-2.29) | 1.21 (0.94-1.54) | 1.27 (0.70-2.31) | 0.77 (0.42-1.39) |
| Memory | 1.29 (1.04-1.59) | 0.86 (0.46-1.62) | 1.02 (0.77-1.35) | 0.61 (0.28-1.35) | 1.89 (1.02-3.48) |
| Psychosocial factors‡ | |||||
| Anxiety | 0.73 (0.57-0.95) | 0.68 (0.35-1.31) | 0.71 (0.51-0.99) | 0.88 (0.35-2.22) | 0.37 (0.17-0.81) |
| Depression | 1.24 (1.01-1.53) | 1.79 (1.02-3.15) | 1.30 (0.98-1.74) | 0.68 (0.29-1.56) | 1.87 (1.01-3.46) |
| Quality of life measures | |||||
| General health | 1.10 (0.89-1.35) | 1.29 (0.84-1.97) | 1.10 (0.85-1.41) | 1.16 (0.74-1.83) | 1.49 (0.91-2.46) |
| Physical function | 1.12 (0.84-1.48) | 1.12 (0.62-2.04) | 1.42 (1.04-1.94) | 1.35 (0.70-2.63) | 2.24 (1.30-3.85) |
| Physical role limitation | 1.10 (0.84-1.44) | 1.13 (0.65-1.97) | 1.96 (1.44-2.66) | 1.71 (0.92-3.18) | 4.06 (2.36-7.00) |
| Pain | 1.27 (1.00-1.62) | 0.97 (0.57-1.63) | 1.04 (0.78-1.38) | 1.03 (0.58-1.83) | 0.97 (0.57-1.65) |
| Emotional role limitation | 0.99 (0.77-1.26) | 1.06 (0.64-1.73) | 0.93 (0.70-1.24) | 0.91 (0.51-1.62) | 1.16 (0.70-1.94) |
| Vitality | 1.02 (0.81-1.28) | 1.35 (0.86-2.13) | 0.99 (0.75-1.29) | 0.76 (0.45-1.28) | 1.26 (0.76-2.08) |
| Social functioning | 1.15 (0.88-1.51) | 1.03 (0.59-1.79) | 0.94 (0.68-1.28) | 0.77 (0.40-1.51) | 1.67 (0.97-2.88) |
| Mental health | 1.07 (0.83-1.38) | 1.26 (0.76-2.08) | 1.15 (0.85-1.54) | 1.17 (0.64-2.14) | 1.4 (0.83-2.36) |
Bold indicates statistical significance (P < .05).
>OR, odds ratio; RR, relative risk.
Log-binomial regression model with modified Poisson adjusted for age at diagnosis, age at follow-up, sex, and race.
Multinomial logistic regression with a 3-level outcome (full-time, part-time, or unemployed) adjusted for age at diagnosis, age at follow-up, sex, race, and somatization.
Neurocognitive and psychosocial factors were evaluated in one model, and quality of life measures were analyzed in a second model.