Table 1. Definition of molecular... | American Society of Hematology

Table 1.

Definition of molecular response to TKI therapy per International Scale (IS)*

PCR^IS	Response
≤1.0%	Complete cytogenetic response (CCyR)
≤0.1%	Major molecular response (MMR)
≤0.01%	Deep molecular response⁴ (MR⁴)
≤0.0032%	Deep molecular response^4.5 (MR^4.5)
≤0.001%	Deep molecular response⁵ (MR⁵)

PCR^IS	Response
≤1.0%	Complete cytogenetic response (CCyR)
≤0.1%	Major molecular response (MMR)
≤0.01%	Deep molecular response⁴ (MR⁴)
≤0.0032%	Deep molecular response^4.5 (MR^4.5)
≤0.001%	Deep molecular response⁵ (MR⁵)

As determined by reverse transcriptase quantitative polymerase chain reaction.