Hematologic features of the individuals in this study
| . | P1 . | P2 . | P3 . | P4 . | P5 . | P6 . | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Hematologic findings . | Reference values . | First available . | Most recent* . | First available . | Most recent . | First available . | Most recent . | First available . | Most recent . | First available . | Most recent . | First available . | Most recent . |
| Blood parameters | |||||||||||||
| Hemoglobin | Age dependent (g/dL) | 6.8 | 7.2 | 10.5 | 10.3 | 7.4 | 10.1 | 3 | 8.1 | 4.5 | 7.1 | 5.6 | 9.4 |
| Reticulocytes | 25-120 (×109/L) | 108 | NA | 87.5 | 32.1 | NA | 96.9 | Decreased | 7.2 | NA | 14 | 127 | 38 |
| MCV | 80-97 fL | 84 | 86 | 81 | 78 | 88 | 94.8 | NA | NA | NA | 86.1 | NA | 80.4 |
| Leukocytes | 4.5-13 (×109/L) | 13.6 | 4.9 | 7.1 | 4.5 | 6.3 | 7.2 | Normal | 7.2 | 10.9 | 5.5 | 5.3 | 8.1 |
| Platelets | 150-450 (×109/L) | 373 | 76 | 239 | 213 | 235 | 248 | Normal | 220 | 269 | 288 | < 10 | 193 |
| HbF | <1% (after 1-2 y of age) | NA | NA | NA | 3.3 | NA | NA | NA | NA | NA | 1.0 | NA | 1.4 |
| eADA | <1.4 (U/g Hb) | NA | NA | 8.3 | NA | NA | 12.8 | NA | NA | NA | NA | NA | 4.02 |
| Bone marrow findings | |||||||||||||
| Erythroid lineage | Decreased | Decreased | Decreased | Decreased | Decreased | Decreased | |||||||
| Dyserythropoiesis | No | No | No | No | No | No | |||||||
| Megakaryocytic lineage | Normal | Normal | Normal | Normal | Normal | Normal | |||||||
| Remarks | Some monolobulated megakaryocytes, normal size | Some monolobulated megakaryocytes, normal size | |||||||||||
| . | P1 . | P2 . | P3 . | P4 . | P5 . | P6 . | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Hematologic findings . | Reference values . | First available . | Most recent* . | First available . | Most recent . | First available . | Most recent . | First available . | Most recent . | First available . | Most recent . | First available . | Most recent . |
| Blood parameters | |||||||||||||
| Hemoglobin | Age dependent (g/dL) | 6.8 | 7.2 | 10.5 | 10.3 | 7.4 | 10.1 | 3 | 8.1 | 4.5 | 7.1 | 5.6 | 9.4 |
| Reticulocytes | 25-120 (×109/L) | 108 | NA | 87.5 | 32.1 | NA | 96.9 | Decreased | 7.2 | NA | 14 | 127 | 38 |
| MCV | 80-97 fL | 84 | 86 | 81 | 78 | 88 | 94.8 | NA | NA | NA | 86.1 | NA | 80.4 |
| Leukocytes | 4.5-13 (×109/L) | 13.6 | 4.9 | 7.1 | 4.5 | 6.3 | 7.2 | Normal | 7.2 | 10.9 | 5.5 | 5.3 | 8.1 |
| Platelets | 150-450 (×109/L) | 373 | 76 | 239 | 213 | 235 | 248 | Normal | 220 | 269 | 288 | < 10 | 193 |
| HbF | <1% (after 1-2 y of age) | NA | NA | NA | 3.3 | NA | NA | NA | NA | NA | 1.0 | NA | 1.4 |
| eADA | <1.4 (U/g Hb) | NA | NA | 8.3 | NA | NA | 12.8 | NA | NA | NA | NA | NA | 4.02 |
| Bone marrow findings | |||||||||||||
| Erythroid lineage | Decreased | Decreased | Decreased | Decreased | Decreased | Decreased | |||||||
| Dyserythropoiesis | No | No | No | No | No | No | |||||||
| Megakaryocytic lineage | Normal | Normal | Normal | Normal | Normal | Normal | |||||||
| Remarks | Some monolobulated megakaryocytes, normal size | Some monolobulated megakaryocytes, normal size | |||||||||||
eADA, erythrocyte adenosine deaminase; Hb, hemoglobin; HbF, fetal hemoglobin; MCV, mean corpuscular volume; NA, not available.
During last phase of treatment for osteosarcoma.