Demographics, offspring HLA-C, and maternal KIR carrier frequencies among case and control mother-child pairs in CCRLP and CCLS
| . | Latino all races . | Non-Latino White . | Non-Latino Asian . | Non-Latino Black . | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Case (N = 139) . | Control (N = 251) . | P* . | Case (N = 56) . | Control (N = 104) . | P* . | Case (N = 27) . | Control (N = 37) . | P* . | Case (N = 4) . | Control (N = 12) . | P* . | |
| Study† | NA | NA | NA | NA | ||||||||
| CCRLP | 76 (54.7%) | 251 (100%) | 38 (67.9%) | 104 (100%) | 12 (44.4%) | 37 (100%) | 0 (0%) | 12 (100%) | ||||
| CCLS | 63 (45.3%) | 0 (0%) | 18 (32.1%) | 0 (0%) | 15 (55.6%) | 0 (0%) | 4 (100%) | 0 (0%) | ||||
| Offspring sex | .449 | .165 | .396 | 1.000 | ||||||||
| Female | 53 (38.1%) | 107 (42.6%) | 27 (48.2%) | 37 (35.6%) | 8 (29.6%) | 16 (43.2%) | 1 (25.0%) | 3 (25.0%) | ||||
| Male | 86 (61.9%) | 144 (57.4%) | 29 (51.8%) | 67 (64.4%) | 19 (70.4%) | 21 (56.8%) | 3 (75.0%) | 9 (75.0%) | ||||
| Offspring HLAC | .128 | .371 | .067 | .334 | ||||||||
| C1/C1 | 47 (33.8%) | 101 (40.2%) | 16 (28.6%) | 41 (39.4%) | 10 (37.0%) | 15 (40.5%) | 2 (50.0%) | 3 (25.0%) | ||||
| C1/C2 | 60 (43.2%) | 112 (44.6%) | 31 (55.4%) | 47 (45.2%) | 9 (33.3%) | 19 (51.4%) | 1 (25.0%) | 8 (66.7%) | ||||
| C2/C2 | 32 (23.0%) | 38 (15.1%) | 9 (16.1%) | 16 (15.4%) | 8 (29.6%) | 3 (8.1%) | 1 (25.0%) | 1 (8.3%) | ||||
| Maternal KIR | .002 | .939 | .139 | .120 | ||||||||
| A/A | 22 (15.8%) | 14 (5.6%) | 6 (10.7%) | 13 (12.5%) | 3 (11.1%) | 0 (0%) | 3 (75.0%) | 2 (16.7%) | ||||
| B/x | 117 (84.2%) | 237 (94.4%) | 50 (89.3%) | 91 (87.5%) | 24 (88.9%) | 37 (100%) | 1 (25.0%) | 10 (83.3%) | ||||
| Activation score | <.001 | .981 | .040 | <.001 | ||||||||
| Mean (SD) | 1.58 (1.34) | 2.44 (1.26) | 2.05 (1.52) | 2.05 (1.12) | 1.89 (1.45) | 2.62 (1.26) | 0 (0) | 1.92 (1.38) | ||||
| Inhibition score | .003 | .727 | .566 | .027 | ||||||||
| Mean (SD) | 3.41 (0.996) | 3.73 (1.03) | 3.84 (1.15) | 3.90 (1.05) | 3.52 (1.03) | 3.68 (1.13) | 2.88 (0.854) | 4.38 (1.09) | ||||
| . | Latino all races . | Non-Latino White . | Non-Latino Asian . | Non-Latino Black . | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Case (N = 139) . | Control (N = 251) . | P* . | Case (N = 56) . | Control (N = 104) . | P* . | Case (N = 27) . | Control (N = 37) . | P* . | Case (N = 4) . | Control (N = 12) . | P* . | |
| Study† | NA | NA | NA | NA | ||||||||
| CCRLP | 76 (54.7%) | 251 (100%) | 38 (67.9%) | 104 (100%) | 12 (44.4%) | 37 (100%) | 0 (0%) | 12 (100%) | ||||
| CCLS | 63 (45.3%) | 0 (0%) | 18 (32.1%) | 0 (0%) | 15 (55.6%) | 0 (0%) | 4 (100%) | 0 (0%) | ||||
| Offspring sex | .449 | .165 | .396 | 1.000 | ||||||||
| Female | 53 (38.1%) | 107 (42.6%) | 27 (48.2%) | 37 (35.6%) | 8 (29.6%) | 16 (43.2%) | 1 (25.0%) | 3 (25.0%) | ||||
| Male | 86 (61.9%) | 144 (57.4%) | 29 (51.8%) | 67 (64.4%) | 19 (70.4%) | 21 (56.8%) | 3 (75.0%) | 9 (75.0%) | ||||
| Offspring HLAC | .128 | .371 | .067 | .334 | ||||||||
| C1/C1 | 47 (33.8%) | 101 (40.2%) | 16 (28.6%) | 41 (39.4%) | 10 (37.0%) | 15 (40.5%) | 2 (50.0%) | 3 (25.0%) | ||||
| C1/C2 | 60 (43.2%) | 112 (44.6%) | 31 (55.4%) | 47 (45.2%) | 9 (33.3%) | 19 (51.4%) | 1 (25.0%) | 8 (66.7%) | ||||
| C2/C2 | 32 (23.0%) | 38 (15.1%) | 9 (16.1%) | 16 (15.4%) | 8 (29.6%) | 3 (8.1%) | 1 (25.0%) | 1 (8.3%) | ||||
| Maternal KIR | .002 | .939 | .139 | .120 | ||||||||
| A/A | 22 (15.8%) | 14 (5.6%) | 6 (10.7%) | 13 (12.5%) | 3 (11.1%) | 0 (0%) | 3 (75.0%) | 2 (16.7%) | ||||
| B/x | 117 (84.2%) | 237 (94.4%) | 50 (89.3%) | 91 (87.5%) | 24 (88.9%) | 37 (100%) | 1 (25.0%) | 10 (83.3%) | ||||
| Activation score | <.001 | .981 | .040 | <.001 | ||||||||
| Mean (SD) | 1.58 (1.34) | 2.44 (1.26) | 2.05 (1.52) | 2.05 (1.12) | 1.89 (1.45) | 2.62 (1.26) | 0 (0) | 1.92 (1.38) | ||||
| Inhibition score | .003 | .727 | .566 | .027 | ||||||||
| Mean (SD) | 3.41 (0.996) | 3.73 (1.03) | 3.84 (1.15) | 3.90 (1.05) | 3.52 (1.03) | 3.68 (1.13) | 2.88 (0.854) | 4.38 (1.09) | ||||