HRs and 95% CIs for the association between patient characteristics and OS
| . | . | Univariable model . | Multivariable model . | ||
|---|---|---|---|---|---|
| Patient characteristics . | N (event N) . | HR (95% CI) . | P . | HR (95% CI) . | P . |
| Race and ethnicity | |||||
| Non-Hispanic White | 398 (184) | 1.00 (referent) | 1.00 (referent) | ||
| Non-Hispanic Black | 52 (19) | 0.50 (0.31, 0.81) | .005 | 0.62 (0.37, 1.03) | .06 |
| Hispanic | 45 (12) | 0.66 (0.37, 1.19) | .2 | 0.76 (0.42, 1.38) | .4 |
| Age at MM diagnosis* | 495 (215) | 1.05 (1.04, 1.07) | <.001 | 1.04 (1.02, 1.05) | <.001 |
| Sex | |||||
| Female | 206 (85) | 1.00 (referent) | 1.00 (referent) | ||
| Male | 289 (130) | 1.25 (0.95, 1.65) | .1 | 1.19 (0.89, 1.57) | .2 |
| ISS at MM diagnosis | |||||
| I | 190 (67) | 1.00 (referent) | 1.00 (referent) | ||
| II | 123 (55) | 1.45 (1.02, 2.08) | .04 | 1.49 (1.04, 2.13) | .03 |
| III | 111 (54) | 1.49 (1.04, 2.14) | .03 | 1.33 (0.92, 1.92) | .1 |
| Unknown | 71 (39) | 0.86 (0.57, 1.29) | .5 | 0.80 (0.53, 1.21) | .3 |
| HCT | |||||
| No HCT | 198 (90) | 1.00 (referent) | 1.00 (referent) | ||
| HCT | 297 (125) | 0.50 (0.38, 0.66) | <.001 | 0.65 (0.47, 0.89) | .008 |
| Frontline treatment† | |||||
| PI + IMIDs | 197 (58) | 1.00 (referent) | 1.00 (referent) | ||
| PI | 165 (89) | 1.47 (1.06, 2.05) | .02 | 1.44 (1.03, 2.02) | .03 |
| IMIDs | 107 (52) | 0.83 (0.56, 1.22) | .3 | 0.75 (0.51, 1.10) | .1 |
| Others | 26 (16) | 0.56 (0.31, 1.02) | .06 | 0.67 (0.36, 1.23) | .2 |
| . | . | Univariable model . | Multivariable model . | ||
|---|---|---|---|---|---|
| Patient characteristics . | N (event N) . | HR (95% CI) . | P . | HR (95% CI) . | P . |
| Race and ethnicity | |||||
| Non-Hispanic White | 398 (184) | 1.00 (referent) | 1.00 (referent) | ||
| Non-Hispanic Black | 52 (19) | 0.50 (0.31, 0.81) | .005 | 0.62 (0.37, 1.03) | .06 |
| Hispanic | 45 (12) | 0.66 (0.37, 1.19) | .2 | 0.76 (0.42, 1.38) | .4 |
| Age at MM diagnosis* | 495 (215) | 1.05 (1.04, 1.07) | <.001 | 1.04 (1.02, 1.05) | <.001 |
| Sex | |||||
| Female | 206 (85) | 1.00 (referent) | 1.00 (referent) | ||
| Male | 289 (130) | 1.25 (0.95, 1.65) | .1 | 1.19 (0.89, 1.57) | .2 |
| ISS at MM diagnosis | |||||
| I | 190 (67) | 1.00 (referent) | 1.00 (referent) | ||
| II | 123 (55) | 1.45 (1.02, 2.08) | .04 | 1.49 (1.04, 2.13) | .03 |
| III | 111 (54) | 1.49 (1.04, 2.14) | .03 | 1.33 (0.92, 1.92) | .1 |
| Unknown | 71 (39) | 0.86 (0.57, 1.29) | .5 | 0.80 (0.53, 1.21) | .3 |
| HCT | |||||
| No HCT | 198 (90) | 1.00 (referent) | 1.00 (referent) | ||
| HCT | 297 (125) | 0.50 (0.38, 0.66) | <.001 | 0.65 (0.47, 0.89) | .008 |
| Frontline treatment† | |||||
| PI + IMIDs | 197 (58) | 1.00 (referent) | 1.00 (referent) | ||
| PI | 165 (89) | 1.47 (1.06, 2.05) | .02 | 1.44 (1.03, 2.02) | .03 |
| IMIDs | 107 (52) | 0.83 (0.56, 1.22) | .3 | 0.75 (0.51, 1.10) | .1 |
| Others | 26 (16) | 0.56 (0.31, 1.02) | .06 | 0.67 (0.36, 1.23) | .2 |