Average protofibril lengths
| . | 10 min . | 20 min . |
|---|---|---|
| WT | 190 ± 71 nm | 250 ± 147 nm |
| γDEK | 163 ± 54 nm | 221 ± 128 nm |
| γD297N | 152 ± 73 nm* | 291 ± 191 nm |
| γE323Q | 184 ± 82 nm | 256 ± 163 nm |
| γK356Q | 218 ± 110 nm* | 286 ± 134 nm |
| . | 10 min . | 20 min . |
|---|---|---|
| WT | 190 ± 71 nm | 250 ± 147 nm |
| γDEK | 163 ± 54 nm | 221 ± 128 nm |
| γD297N | 152 ± 73 nm* | 291 ± 191 nm |
| γE323Q | 184 ± 82 nm | 256 ± 163 nm |
| γK356Q | 218 ± 110 nm* | 286 ± 134 nm |
Results are presented as mean ± standard deviation. Greater than 20 protofibrils were measured per condition over 3 independent experiments.
P < .05 vs WT at the same time point.