Patient, disease and transplant characteristics
| Variable . | Median (range) or N (%) . |
|---|---|
| Patient sex | |
| Female | 12 (39) |
| Male | 19 (61) |
| Patient’s age at transplant (y) | 37 (21-58) |
| Donor’s age at transplant (y), n = 30 | 29 (12-68) |
| Sex of donor/recipient | |
| Female/male | 7 (23) |
| Other | 24 (77) |
| Number of mismatches | 5 (2-6) |
| Disease diagnosis | |
| AML | 17 (55) |
| ALL | 13 (42) |
| MDS | 1 (3) |
| Cytogenetic risk at diagnosis | |
| AML* | |
| Intermediate | 8 (26) |
| Advance | 9 (29) |
| ALL† | |
| Favorable | 3 (10) |
| Unfavorable | 10 (32) |
| MDS‡ | |
| High risk | 1 (3) |
| Disease status before conditioning | |
| AML/ALL | |
| CR1 with poor risk cytogenetics | 14 (45) |
| CR2/CR3 | 9 (29.5) |
| Active disease | 7 (22.5) |
| MDS | |
| High risk relapsed | 1 (3) |
| Time from diagnosis to transplant (mo) | 7.1 (2.7-62.7) |
| Donor CMV status | |
| Negative | 11 (35) |
| Positive | 20 (65) |
| Patient CMV status | |
| Negative | 4 (13) |
| Positive | 27 (87) |
| HCT comorbidity index | 1 (0-6) |
| 0 | 14 (45) |
| 1-2 | 9 (29) |
| ≥3 | 8 (26) |
| Disease risk iIndex | |
| Low | 1 (3) |
| Intermediate | 11 (35) |
| High | 12 (39) |
| Very high | 7 (23) |
| Karnofsky performance status at HCT | |
| ≥80 | 31 (100) |
| Variable . | Median (range) or N (%) . |
|---|---|
| Patient sex | |
| Female | 12 (39) |
| Male | 19 (61) |
| Patient’s age at transplant (y) | 37 (21-58) |
| Donor’s age at transplant (y), n = 30 | 29 (12-68) |
| Sex of donor/recipient | |
| Female/male | 7 (23) |
| Other | 24 (77) |
| Number of mismatches | 5 (2-6) |
| Disease diagnosis | |
| AML | 17 (55) |
| ALL | 13 (42) |
| MDS | 1 (3) |
| Cytogenetic risk at diagnosis | |
| AML* | |
| Intermediate | 8 (26) |
| Advance | 9 (29) |
| ALL† | |
| Favorable | 3 (10) |
| Unfavorable | 10 (32) |
| MDS‡ | |
| High risk | 1 (3) |
| Disease status before conditioning | |
| AML/ALL | |
| CR1 with poor risk cytogenetics | 14 (45) |
| CR2/CR3 | 9 (29.5) |
| Active disease | 7 (22.5) |
| MDS | |
| High risk relapsed | 1 (3) |
| Time from diagnosis to transplant (mo) | 7.1 (2.7-62.7) |
| Donor CMV status | |
| Negative | 11 (35) |
| Positive | 20 (65) |
| Patient CMV status | |
| Negative | 4 (13) |
| Positive | 27 (87) |
| HCT comorbidity index | 1 (0-6) |
| 0 | 14 (45) |
| 1-2 | 9 (29) |
| ≥3 | 8 (26) |
| Disease risk iIndex | |
| Low | 1 (3) |
| Intermediate | 11 (35) |
| High | 12 (39) |
| Very high | 7 (23) |
| Karnofsky performance status at HCT | |
| ≥80 | 31 (100) |