Patient and BMT characteristics by haploidentical and MUD BMT in the propensity-matched cohort
| Variables . | Propensity score matching cohort in (RIC + MA) . | P value . | ||
|---|---|---|---|---|
| Matched (n = 837) . | MUD (n = 200) . | Haplo (n = 637) . | ||
| Age at BMT | ||||
| Median (range) | 58 (18-80) | 60 (18-80) | 58 (19-78) | .07 |
| Race, n (%) | .41 | |||
| Caucasian | 742 (89) | 181 (91) | 561 (88) | |
| Other | 95 (11) | 19 (9) | 76 (12) | |
| Gender, n (%) | .86 | |||
| Female | 467 (56) | 110 (55) | 357 (56) | |
| Male | 370 (44) | 90 (45) | 280 (44) | |
| BMT Year, n (%) | .86 | |||
| 2011-2014 | 93 (11) | 21 (11) | 72 (11) | |
| 2015-2018 | 744 (89) | 179 (89) | 565 (89) | |
| Dx to BMT (month) | 10.15 (13.34) | 10.55 (16.22) | 10.02 (12.31) | .67 |
| Median (range) | 5.9 (1.45 165.16) | 5.92 (1.45 165.16) | 5.95 (1.61, 112.89) | .85 |
| Disease, n (%) | .71 | |||
| ALL | 201 (24) | 45 (22) | 156 (25) | |
| AML | 455 (54) | 108 (54) | 347 (54) | |
| MDS | 181 (22) | 47 (24) | 134 (21) | |
| Condition, n (%) | .44 | |||
| RIC | 455 (54) | 114 (57) | 341 (54) | |
| MAC | 382 (46) | 86 (43) | 296 (46) | |
| TBI, n (%) | .07 | |||
| No | 329 (39) | 90 (45) | 239 (38) | |
| Yes | 508 (61) | 110 (55) | 398 (62) | |
| Transplant source, n (%) | .84 | |||
| BM | 140 (17) | 32 (16) | 108 (17) | |
| PB | 697 (83) | 168 (84) | 529 (83) | |
| HCT, n (%) | .68 | |||
| ≤2 | 385 (46) | 89 (44.5) | 296 (47) | |
| ≥3 | 452 (54) | 111 (55.5) | 341 (53) | |
| KPS, n (%) | .73 | |||
| <90 | 504 (60) | 123 (62) | 381 (60) | |
| 90-100 | 333 (40) | 77 (38) | 256 (40) | |
| DRI, n (%) | .54 | |||
| Low/intermediate | 692 (83) | 162 (81) | 530 (83) | |
| High/very high | 145 (17) | 38 (19) | 107 (17) | |
| Recip. CMV, n (%) | .32 | |||
| Negative | 300 (36) | 78 (39) | 222 (35) | |
| Positive | 537 (64) | 122 (61) | 415 (65) | |
| Donor age | ||||
| Median (range) | 30 (13-71) | 29 (19-60) | 30 (13-71) | .84 |
| Variables . | Propensity score matching cohort in (RIC + MA) . | P value . | ||
|---|---|---|---|---|
| Matched (n = 837) . | MUD (n = 200) . | Haplo (n = 637) . | ||
| Age at BMT | ||||
| Median (range) | 58 (18-80) | 60 (18-80) | 58 (19-78) | .07 |
| Race, n (%) | .41 | |||
| Caucasian | 742 (89) | 181 (91) | 561 (88) | |
| Other | 95 (11) | 19 (9) | 76 (12) | |
| Gender, n (%) | .86 | |||
| Female | 467 (56) | 110 (55) | 357 (56) | |
| Male | 370 (44) | 90 (45) | 280 (44) | |
| BMT Year, n (%) | .86 | |||
| 2011-2014 | 93 (11) | 21 (11) | 72 (11) | |
| 2015-2018 | 744 (89) | 179 (89) | 565 (89) | |
| Dx to BMT (month) | 10.15 (13.34) | 10.55 (16.22) | 10.02 (12.31) | .67 |
| Median (range) | 5.9 (1.45 165.16) | 5.92 (1.45 165.16) | 5.95 (1.61, 112.89) | .85 |
| Disease, n (%) | .71 | |||
| ALL | 201 (24) | 45 (22) | 156 (25) | |
| AML | 455 (54) | 108 (54) | 347 (54) | |
| MDS | 181 (22) | 47 (24) | 134 (21) | |
| Condition, n (%) | .44 | |||
| RIC | 455 (54) | 114 (57) | 341 (54) | |
| MAC | 382 (46) | 86 (43) | 296 (46) | |
| TBI, n (%) | .07 | |||
| No | 329 (39) | 90 (45) | 239 (38) | |
| Yes | 508 (61) | 110 (55) | 398 (62) | |
| Transplant source, n (%) | .84 | |||
| BM | 140 (17) | 32 (16) | 108 (17) | |
| PB | 697 (83) | 168 (84) | 529 (83) | |
| HCT, n (%) | .68 | |||
| ≤2 | 385 (46) | 89 (44.5) | 296 (47) | |
| ≥3 | 452 (54) | 111 (55.5) | 341 (53) | |
| KPS, n (%) | .73 | |||
| <90 | 504 (60) | 123 (62) | 381 (60) | |
| 90-100 | 333 (40) | 77 (38) | 256 (40) | |
| DRI, n (%) | .54 | |||
| Low/intermediate | 692 (83) | 162 (81) | 530 (83) | |
| High/very high | 145 (17) | 38 (19) | 107 (17) | |
| Recip. CMV, n (%) | .32 | |||
| Negative | 300 (36) | 78 (39) | 222 (35) | |
| Positive | 537 (64) | 122 (61) | 415 (65) | |
| Donor age | ||||
| Median (range) | 30 (13-71) | 29 (19-60) | 30 (13-71) | .84 |
CMV, cytomegalovirus; Dx, diagnosis; BM, bone marrow; PB, peripheral blood; HCT, recipient Sorror comorbidity score; Recip. CMV, recipient CMV serostatus.