Algorithm performance characteristics in the validation cohort
| . | Sensitivity (%) . | Specificity (%) . | PPV (%) . | NPV (%) . | Threshold . |
|---|---|---|---|---|---|
| TNFR1 + TIM3 | 44.2 | 61.3 | 15.4 | 87.3 | 0.21 |
| TNFR1 + ST2 | 57.7 | 79.8 | 31.3 | 92.2 | 0.22 |
| TNFR1 + REG3α | 84.6 | 47.9 | 20.6 | 95.1 | 0.16 |
| ST2 + REG3α | 75.0 | 76.1 | 33.3 | 95.0 | 0.21 |
| . | Sensitivity (%) . | Specificity (%) . | PPV (%) . | NPV (%) . | Threshold . |
|---|---|---|---|---|---|
| TNFR1 + TIM3 | 44.2 | 61.3 | 15.4 | 87.3 | 0.21 |
| TNFR1 + ST2 | 57.7 | 79.8 | 31.3 | 92.2 | 0.22 |
| TNFR1 + REG3α | 84.6 | 47.9 | 20.6 | 95.1 | 0.16 |
| ST2 + REG3α | 75.0 | 76.1 | 33.3 | 95.0 | 0.21 |