Multivariate analysis by Cox regression
| Multivariate PFS . | |||
|---|---|---|---|
| . | HR . | P . | 95% CI . |
| Bridging nonresponder (vs bridging responder) | 2.273 | <.001 | 1.484-3.481 |
| No bridging (vs bridging responder) | 1.563 | .0871 | 0.937-2.607 |
| LDH at LD (>N vs N) | 1.443 | .011 | 1.087-1.916 |
| ECOG (0, 1, 2, 3, 4) | 1.180 | .055 | 0.997-1.398 |
| Tisa-cel (vs axi-cel) | 1.475 | .005 | 1.122-1.942 |
| Age (decades) | 0.904 | .024 | 0.825-0.990 |
| Multivariate PFS . | |||
|---|---|---|---|
| . | HR . | P . | 95% CI . |
| Bridging nonresponder (vs bridging responder) | 2.273 | <.001 | 1.484-3.481 |
| No bridging (vs bridging responder) | 1.563 | .0871 | 0.937-2.607 |
| LDH at LD (>N vs N) | 1.443 | .011 | 1.087-1.916 |
| ECOG (0, 1, 2, 3, 4) | 1.180 | .055 | 0.997-1.398 |
| Tisa-cel (vs axi-cel) | 1.475 | .005 | 1.122-1.942 |
| Age (decades) | 0.904 | .024 | 0.825-0.990 |
| Multivariate OS . | |||
|---|---|---|---|
| . | HR* . | P . | 95% CI . |
| Bridging nonresponder (vs bridging responder) | 2.273 | .003 | 1.324-3.901 |
| No bridging (vs bridging responder) | 1.032 | .925 | 0.531-2.008 |
| LDH at LD (>N vs N) | 1.439 | .038 | 1.021-2.028 |
| ECOG (0, 1, 2, 3, 4)* | 1.357 | .003 | 1.107-1.663 |
| Multivariate OS . | |||
|---|---|---|---|
| . | HR* . | P . | 95% CI . |
| Bridging nonresponder (vs bridging responder) | 2.273 | .003 | 1.324-3.901 |
| No bridging (vs bridging responder) | 1.032 | .925 | 0.531-2.008 |
| LDH at LD (>N vs N) | 1.439 | .038 | 1.021-2.028 |
| ECOG (0, 1, 2, 3, 4)* | 1.357 | .003 | 1.107-1.663 |
ECOG, Eastern Cooperative Oncology Group performance status; LD, lymphodepletion; LDH, lactate dehydrogenase; N, normal.
HR refers to change of 1 point in score.