Normal hematologic values during the first year of life in healthy term infants*
| . | Age (mo) . | ||||||
|---|---|---|---|---|---|---|---|
| . | 0.5 (n = 232) . | 1 (n = 240) . | 2 (n = 241) . | 4 (n = 52) . | 6 (n = 52) . | 9 (n = 56) . | 12 (n = 56) . |
| Hb (g/dL, mean ± SE), (−2 SD) | 16.6 ± 6 0.11 (13.4) | 13.9 ± 0.10 (10.7) | 11.2 ± 0.06 (9.4) | 12.2 ± 0.14 (10.3) | 12.6 ± 0.10 (11.1) | 12.7 ± 0.09 (11.4) | 12.7 ± 0.09 (11.3) |
| Hematocrit (%, mean ± SE), (−2 SD) | 53 ± 0.4 (41) | 44 ± 0.3 (33) | 35 ± 0.2 (28) | 38 ± 0.4 (32) | 36 ± 0.3 (31) | 36 ± 0.3 (32) | 37 ± 0.3 (33) |
| RBC count (×1012/L, mean ± SE), (−2 SD + 2 SD) | 4.9 ± 0.03 (3.9-5.9) | 4.3 ± 0.03 (3.3-5.3) | 3.7 ± 0.02 (3.1-4.3) | 4.3 ± 0.06 (3.5-5.1) | 4.7 ± 0.05 (3.9-5.5) | 4.7 ± 0.04 (4.0-5.3) | 4.7 ± 0.04 (4.1-5.3) |
| MCH (pg, mean ± SE), (−2 SD) | 33.6 ± 0.1 (30) | 32.5 ± 0.1 (29) | 30.4 ± 0.1 (27) | 28.6 ± 0.2 (25) | 26.8 ± 0.2 (24) | 27.3 ± 0.2 (25) | 26.8 ± 0.2 (24) |
| MCV (fL, mean ± SE), (−2 SD) | 105.3 ± 0.6 (88) | 101.3 ± 0.3 (91) | 94.8 ± 0.3 (84) | 86.7 ± 0.8 (76) | 76.3 ± 0.6 (68) | 77.7 ± 0.5 (70) | 77.7 ± 0.5 (71) |
| MCHC (g/dL, mean ± SE), (−2 SD) | 314 ± 1.1 (281) | 318 ± 1.2 (281) | 318 ± 1.1 (283) | 327 ± 2.7 (288) | 350 ± 1.7 (327) | 349 ± 1.6 (324) | 343 ± 1.5 (321) |
| . | Age (mo) . | ||||||
|---|---|---|---|---|---|---|---|
| . | 0.5 (n = 232) . | 1 (n = 240) . | 2 (n = 241) . | 4 (n = 52) . | 6 (n = 52) . | 9 (n = 56) . | 12 (n = 56) . |
| Hb (g/dL, mean ± SE), (−2 SD) | 16.6 ± 6 0.11 (13.4) | 13.9 ± 0.10 (10.7) | 11.2 ± 0.06 (9.4) | 12.2 ± 0.14 (10.3) | 12.6 ± 0.10 (11.1) | 12.7 ± 0.09 (11.4) | 12.7 ± 0.09 (11.3) |
| Hematocrit (%, mean ± SE), (−2 SD) | 53 ± 0.4 (41) | 44 ± 0.3 (33) | 35 ± 0.2 (28) | 38 ± 0.4 (32) | 36 ± 0.3 (31) | 36 ± 0.3 (32) | 37 ± 0.3 (33) |
| RBC count (×1012/L, mean ± SE), (−2 SD + 2 SD) | 4.9 ± 0.03 (3.9-5.9) | 4.3 ± 0.03 (3.3-5.3) | 3.7 ± 0.02 (3.1-4.3) | 4.3 ± 0.06 (3.5-5.1) | 4.7 ± 0.05 (3.9-5.5) | 4.7 ± 0.04 (4.0-5.3) | 4.7 ± 0.04 (4.1-5.3) |
| MCH (pg, mean ± SE), (−2 SD) | 33.6 ± 0.1 (30) | 32.5 ± 0.1 (29) | 30.4 ± 0.1 (27) | 28.6 ± 0.2 (25) | 26.8 ± 0.2 (24) | 27.3 ± 0.2 (25) | 26.8 ± 0.2 (24) |
| MCV (fL, mean ± SE), (−2 SD) | 105.3 ± 0.6 (88) | 101.3 ± 0.3 (91) | 94.8 ± 0.3 (84) | 86.7 ± 0.8 (76) | 76.3 ± 0.6 (68) | 77.7 ± 0.5 (70) | 77.7 ± 0.5 (71) |
| MCHC (g/dL, mean ± SE), (−2 SD) | 314 ± 1.1 (281) | 318 ± 1.2 (281) | 318 ± 1.1 (283) | 327 ± 2.7 (288) | 350 ± 1.7 (327) | 349 ± 1.6 (324) | 343 ± 1.5 (321) |
Values at the ages of 0.5, 1, and 2 mo were obtained from the entire group, and those at the later ages were obtained from the iron supplemented infant group after exclusion of iron deficiency.121
These values were obtained from a selected group of 256 healthy term infants followed at the Helsinki University Central Hospital who were receiving continuous iron supplementation and who had normal values for transferrin saturation and serum ferritin.