Table 2.

Characteristics of patients with relapses and rescue treatments

Patients, n (%) 9 (31) 
Median time to recurrence (from irradiation) (mo): median (IQR, 25-75] 8.7 [4-11.5] 
Pattern of recurrence, n (%)  
 Unifocal 4 (44) 
 Multifocal 5 (56) 
Site of recurrence, n (%)  
 Initial 1 (12) 
 Distant 8 (88) 
Second-line chemotherapy, n  
 R-ICE 
 Other (IVA, ibrutinib, R-lenalidomide, R-MBVP) 
IC-ASCT, n (%) 5 (55) 
 At first recurrence 
 Later 
Patients, n (%) 9 (31) 
Median time to recurrence (from irradiation) (mo): median (IQR, 25-75] 8.7 [4-11.5] 
Pattern of recurrence, n (%)  
 Unifocal 4 (44) 
 Multifocal 5 (56) 
Site of recurrence, n (%)  
 Initial 1 (12) 
 Distant 8 (88) 
Second-line chemotherapy, n  
 R-ICE 
 Other (IVA, ibrutinib, R-lenalidomide, R-MBVP) 
IC-ASCT, n (%) 5 (55) 
 At first recurrence 
 Later 

IVA, ifosfamide, vincristine, actinomycin; R-ICE, rituximab, ifosfamide, carboplatin, etoposide.

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