Patient characteristics: analysis B
. | CHOP . | CHOEP . | ||
---|---|---|---|---|
n . | % . | n . | % . | |
ALK+ ALCL | (n = 28) | (n = 30) | ||
Male sex | 18 | 64 | 16 | 53 |
Age at diagnosis, y | ||||
Median | 43 | 49 | ||
Range | 23-63 | 19-62 | ||
Ann Arbor stage | ||||
2 | 8 | 29 | 10 | 33 |
3-4 | 20 | 71 | 20 | 67 |
Elevated LDH | 7 | 25 | 10 | 33 |
WHO performance score | ||||
0-2 | 14 | 50 | 21 | 70 |
3-4 | 1 | 4 | 1 | 3 |
Unknown | 13 | 46 | 8 | 27 |
>1 extranodal localization | 4 | 14 | 6 | 20 |
IPI score | ||||
0-2 | 26 | 93 | 27 | 90 |
3-5 | 2 | 7 | 3 | 10 |
ALK− ALCL, AITL, or PTCL NOS | (n = 85) | (n = 134) | ||
Male sex | 54 | 64 | 86 | 64 |
Age at diagnosis, y | ||||
Median | 55 | 54 | ||
Range | 26-62 | 19-60 | ||
Subtype of T-cell NHL | ||||
ALK− ALCL | 14 | 16 | 31 | 23 |
ALCL NOS | 0 | — | 1 | 1 |
PTCL NOS | 25 | 29 | 54 | 40 |
AITL* | 46 | 54 | 48 | 36 |
Ann Arbor stage | ||||
2 | 6 | 7 | 14 | 10 |
3-4 | 79 | 93 | 120 | 90 |
Elevated LDH | 48 | 56 | 76 | 57 |
WHO performance score | ||||
0-2 | 38 | 45 | 78 | 58 |
3-4 | 0 | 0 | 4 | 3 |
Unknown | 47 | 55 | 52 | 39 |
>1 extranodal localization | 25 | 29 | 37 | 28 |
IPI score | ||||
0-2 | 52 | 61 | 92 | 69 |
3-5 | 33 | 39 | 42 | 31 |
ASCT | 27 | 32 | 82 | 61 |
. | CHOP . | CHOEP . | ||
---|---|---|---|---|
n . | % . | n . | % . | |
ALK+ ALCL | (n = 28) | (n = 30) | ||
Male sex | 18 | 64 | 16 | 53 |
Age at diagnosis, y | ||||
Median | 43 | 49 | ||
Range | 23-63 | 19-62 | ||
Ann Arbor stage | ||||
2 | 8 | 29 | 10 | 33 |
3-4 | 20 | 71 | 20 | 67 |
Elevated LDH | 7 | 25 | 10 | 33 |
WHO performance score | ||||
0-2 | 14 | 50 | 21 | 70 |
3-4 | 1 | 4 | 1 | 3 |
Unknown | 13 | 46 | 8 | 27 |
>1 extranodal localization | 4 | 14 | 6 | 20 |
IPI score | ||||
0-2 | 26 | 93 | 27 | 90 |
3-5 | 2 | 7 | 3 | 10 |
ALK− ALCL, AITL, or PTCL NOS | (n = 85) | (n = 134) | ||
Male sex | 54 | 64 | 86 | 64 |
Age at diagnosis, y | ||||
Median | 55 | 54 | ||
Range | 26-62 | 19-60 | ||
Subtype of T-cell NHL | ||||
ALK− ALCL | 14 | 16 | 31 | 23 |
ALCL NOS | 0 | — | 1 | 1 |
PTCL NOS | 25 | 29 | 54 | 40 |
AITL* | 46 | 54 | 48 | 36 |
Ann Arbor stage | ||||
2 | 6 | 7 | 14 | 10 |
3-4 | 79 | 93 | 120 | 90 |
Elevated LDH | 48 | 56 | 76 | 57 |
WHO performance score | ||||
0-2 | 38 | 45 | 78 | 58 |
3-4 | 0 | 0 | 4 | 3 |
Unknown | 47 | 55 | 52 | 39 |
>1 extranodal localization | 25 | 29 | 37 | 28 |
IPI score | ||||
0-2 | 52 | 61 | 92 | 69 |
3-5 | 33 | 39 | 42 | 31 |
ASCT | 27 | 32 | 82 | 61 |
Patients receiving CHOP vs CHOEP during first-line treatment.
Including T-cell NHL, follicular helper T cells.