Thrombotic or bleeding events at 100 days
| Outcome . | All (N = 61) . | D-dimer level . | |
|---|---|---|---|
| High (n = 17)* . | Low to moderate (n = 44)* . | ||
| Thrombotic events | |||
| Any thrombosis | 15 (25%) | 9 (53%) | 6 (14%) |
| UE DVT | 6 (40%) | 3 (33%) | 3 (50%) |
| Line-associated UE DVT† | 4 (27%) | 1 (11%) | 3 (50%) |
| LE DVT | 3 (20%) | 3 (33%) | 0 (0%) |
| PE without DVT | 1 (7%) | 1 (11%) | 0 (0%) |
| PE with DVT | 1 (7%) | 0 (0%) | 1 (17%) |
| Ischemic stroke‡ | 4 (27%) | 2 (22%) | 2 (33%) |
| Bleeding events | |||
| Major bleeding | 0 (0%) | 0 (0%) | 0 (0%) |
| Any CRNMB | 3 (5%) | 0 (0%) | 3 (7%) |
| Genitourinary CRNMB | 2 (67%) | 0 (0%) | 2 (67%) |
| Gastrointestinal CRNMB | 1 (33%) | 0 (0%) | 1 (33%) |
| Outcome . | All (N = 61) . | D-dimer level . | |
|---|---|---|---|
| High (n = 17)* . | Low to moderate (n = 44)* . | ||
| Thrombotic events | |||
| Any thrombosis | 15 (25%) | 9 (53%) | 6 (14%) |
| UE DVT | 6 (40%) | 3 (33%) | 3 (50%) |
| Line-associated UE DVT† | 4 (27%) | 1 (11%) | 3 (50%) |
| LE DVT | 3 (20%) | 3 (33%) | 0 (0%) |
| PE without DVT | 1 (7%) | 1 (11%) | 0 (0%) |
| PE with DVT | 1 (7%) | 0 (0%) | 1 (17%) |
| Ischemic stroke‡ | 4 (27%) | 2 (22%) | 2 (33%) |
| Bleeding events | |||
| Major bleeding | 0 (0%) | 0 (0%) | 0 (0%) |
| Any CRNMB | 3 (5%) | 0 (0%) | 3 (7%) |
| Genitourinary CRNMB | 2 (67%) | 0 (0%) | 2 (67%) |
| Gastrointestinal CRNMB | 1 (33%) | 0 (0%) | 1 (33%) |
Including events occurring within 100 days after ALL diagnosis.
LE, lower extremity; PE, pulmonary embolism; UE, upper extremity.
D-dimer level at index: high, ≥4 µg/mL FEU; low to moderate, <4 µg/mL FEU.
DVTs in the UE that were line associated.
Ischemic strokes were diagnosed radiographically (n = 3) or clinically (n = 1).