Drugs, supplements, and comorbidities affecting platelet functiona
Drugs affecting platelet function6 . | |
---|---|
Class . | Examples . |
Aspirin and other nonsteroidal inflammatory drugs | Ibuprofen, naproxen, indomethacin, diclofenac, meclofenamic acid, sulindac, Pepto Bismol |
Glycoprotein IIb/IIIa inhibitors | Abciximab, eptifibatide, tirofiban |
Phosphodiesterase inhibitors | Sildenafil |
β-lactam antibiotics | Penicillins, cephalosporins |
P2Y12 antagonists | Ticlopidine, clopidogrel, prasugrel, ticagrelor |
Selective serotonin reuptake inhibitors | Fluoxetine, paroxetine, sertraline |
Tricyclic antidepressants | Amitriptyline, doxepin, nortriptyline |
Dietary supplements and foods7,8 | |
Dietary supplements such as fish oils containing omega-3 fatty acids, vitamin E, vitamin B3 | |
Herbal supplements such as ginkgo biloba, ginseng, turmeric, cinnamon, tarragon, willow, feverfew, dong quai, meadowsweet, pycnogenol (pine bark extract), guarana | |
Ethanol and nonalcoholic beer | |
Foods (likely only when consumed in large quantities or as a supplement) such as cumin, cloves, onion, garlic, black tree fungus, ginger, aspartame, red/purple grapes (including grape juice, raisins, red wine, grape seeds), green tea, kiwi fruit, tomatoes, blueberries | |
Medical conditions affecting platelet function7 | |
Hematologic disorders such as myeloproliferative neoplasm, myelodysplastic syndrome, paraproteinemia, Gaucher disease | |
Renal failure | |
Liver disease | |
Abnormal cardiac anatomy such as valvular heart disease, left ventricular assistive device, cardiopulmonary bypass | |
Connective tissue diseases such as Ehlers-Danlos |
Drugs affecting platelet function6 . | |
---|---|
Class . | Examples . |
Aspirin and other nonsteroidal inflammatory drugs | Ibuprofen, naproxen, indomethacin, diclofenac, meclofenamic acid, sulindac, Pepto Bismol |
Glycoprotein IIb/IIIa inhibitors | Abciximab, eptifibatide, tirofiban |
Phosphodiesterase inhibitors | Sildenafil |
β-lactam antibiotics | Penicillins, cephalosporins |
P2Y12 antagonists | Ticlopidine, clopidogrel, prasugrel, ticagrelor |
Selective serotonin reuptake inhibitors | Fluoxetine, paroxetine, sertraline |
Tricyclic antidepressants | Amitriptyline, doxepin, nortriptyline |
Dietary supplements and foods7,8 | |
Dietary supplements such as fish oils containing omega-3 fatty acids, vitamin E, vitamin B3 | |
Herbal supplements such as ginkgo biloba, ginseng, turmeric, cinnamon, tarragon, willow, feverfew, dong quai, meadowsweet, pycnogenol (pine bark extract), guarana | |
Ethanol and nonalcoholic beer | |
Foods (likely only when consumed in large quantities or as a supplement) such as cumin, cloves, onion, garlic, black tree fungus, ginger, aspartame, red/purple grapes (including grape juice, raisins, red wine, grape seeds), green tea, kiwi fruit, tomatoes, blueberries | |
Medical conditions affecting platelet function7 | |
Hematologic disorders such as myeloproliferative neoplasm, myelodysplastic syndrome, paraproteinemia, Gaucher disease | |
Renal failure | |
Liver disease | |
Abnormal cardiac anatomy such as valvular heart disease, left ventricular assistive device, cardiopulmonary bypass | |
Connective tissue diseases such as Ehlers-Danlos |
Please note this list is not all inclusive and does not include medications and supplements that can cause thrombocytopenia.